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Efficacy and tolerability balance of oxycodonealoxone and tapentadol in chronic low back pain with a neuropathic component: a blinded end point analysis of randomly selected routine data from 12-week prospective open-label observations

机译：羟考酮/纳洛酮和他喷他多在患有神经病性慢性下腰痛中的功效和耐受性平衡：从12周前瞻性开放标签观察中随机选择的常规数据的盲点分析

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摘要

ObjectiveTo evaluate the benefit–risk profile (BRP) of oxycodonealoxone (OXN) and tapentadol (TAP) in patients with chronic low back pain (cLBP) with a neuropathic component (NC) in routine clinical practice.

机译：目的在常规临床实践中评估羟考酮/纳洛酮（OXN）和他喷他多（TAP）对患有神经病性成分（NC）的慢性下腰痛（cLBP）患者的获益风险曲线（BRP）。

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期刊名称 Journal of Pain Research
作者
Michael A Ueberall; Gerhard H H Mueller-Schwefe;
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年(卷),期 2016(9),-1
年度 2016
页码 1001–1020
总页数 20
原文格式 PDF
正文语种
中图分类基础医学;
关键词
oxycodonealoxone tapentadol chronic low back pain neuropathic component noninterventional study German Pain Registry random data selection blinded end point analysis benefit–risk profile;

机译：羟考酮/纳洛酮;他喷他多;慢性下腰痛;神经病变成分;非干预性研究;德国疼痛注册;随机数据选择;盲点分析;获益-风险特征;

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专利

1. Efficacy and tolerability balance of oxycodonealoxone and tapentadol in chronic low back pain with a neuropathic component: a blinded end point analysis of randomly selected routine data from 12-week prospective open-label observations [J] . Michael A Ueberall, Gerhard H H Mueller-Schwefe Journal of Pain Research . 2016,第4期

机译：羟考酮/纳洛酮和他喷他多在患有神经性疾病的慢性下腰痛中的功效和耐受性平衡：从12周前瞻性开放标签观察中随机选择的常规数据的盲点分析
2. HEALTH-RELATED QUALITY OF LIFE FOR PEOPLE SUFFERING FROM SEVERE CHRONIC LOW BACK PAIN WITH A NEUROPATHIC COMPONENT: RESULTS FROM A POST-HOC ANALYSIS OF RANDOMLY SELECTED ROUTINE DATA, EVALUATED BY RESPONSE TO TREATMENT [J] . Ueberall M. A., Mueller-Schwefe G. H., Essner U. Value in health: the journal of the International Society for Pharmacoeconomics and Outcomes Research . 2016,第7期

机译：重度慢性腰背痛伴神经病患者的生命质量与健康相关：对随机选择的常规数据进行事后分析后得出的结果，该数据是根据对治疗的反应得出的
3. Efficacy and safety of tapentadol extended release for the management of chronic low back pain: results of a prospective, randomized, double-blind, placebo- and active-controlled Phase III study. [J] . Buynak R, Shapiro DY, Okamoto A, Expert opinion on pharmacotherapy . 2010,第11期

机译：他喷他多缓释剂治疗慢性下腰痛的功效和安全性：一项前瞻性，随机，双盲，安慰剂对照和主动控制的III期研究的结果。
4. Development of opioid-induced constipation: post hoc analysis of data from a 12-week prospective open-label blinded-endpoint streamlined study in low-back pain patients treated with prolonged-release WHO step III opioids [O] . Michael A Ueberall, Gerhard HH Mueller-Schwefe 2015

机译：阿片类药物引起的便秘的发展：一项针对12周前瞻性开放标签盲点简化研究的数据的事后分析该研究针对经WHO长期释放的III类阿片类药物治疗的腰痛患者
5. Efficacy and tolerability balance of oxycodone/naloxone and tapentadol in chronic low back pain with a neuropathic component: a blinded end point analysis of randomly selected routine data from 12-week prospective open-label observations [O] . Michael Ueberall, Gerhard Mueller-Schwefe 2016

机译：羟考酮/纳洛酮和Tapentadol的疗效和耐受性平衡在慢性低腰疼痛中具有神经性组分：从12周前瞻性开放标签观测到随机选择的常规数据的盲终点分析

Efficacy and tolerability balance of oxycodonealoxone and tapentadol in chronic low back pain with a neuropathic component: a blinded end point analysis of randomly selected routine data from 12-week prospective open-label observations

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