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Effect of delayed intrathecal administration of capsaicin on neuropathic pain induced by chronic constriction injury of the sciatic nerve in rats

机译：辣椒素鞘内延迟给药对坐骨神经慢性收缩损伤所致神经性疼痛的影响。

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摘要

PurposeThe current study was designed to examine the antinociceptive effect of intrathecally administered capsaicin, a transient receptor potential vanilloid 1 receptor agonist, in a rat model of neuropathic pain induced by unilateral sciatic nerve chronic constriction injury.

机译：目的本研究旨在检查鞘内给予的辣椒素（一种瞬时受体电位类香草酸1受体激动剂）在单侧坐骨神经慢性压迫性损伤引起的神经性疼痛的大鼠模型中的镇痛作用。

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期刊名称 Journal of Pain Research
作者
Kun Zhang; Somayaji Ramamurthy; Thomas J Prihoda; Maxim S Eckmann;
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作者单位

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年(卷),期 2014(7),-1
年度 2014
页码 547–554
总页数 8
原文格式 PDF
正文语种
中图分类基础医学;
关键词
hyperalgesia TRPV1 paw withdrawal latency paw withdrawal threshold;

机译：痛觉过敏;TRPV1;爪退缩潜伏期;爪退缩阈值;

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专利

1. Effect of delayed intrathecal administration of capsaicin on neuropathic pain induced by chronic constriction injury of the sciatic nerve in rats [J] . Kun Zhang, Somayaji Ramamurthy, Thomas J Prihoda, Journal of Pain Research . 2014,第5期

机译：鞘内延迟给予辣椒素对大鼠坐骨神经慢性收缩损伤所致神经性疼痛的影响。
2. Intrathecal leptin inhibits expression of the P2X2/3 receptors and alleviates neuropathic pain induced by chronic constriction sciatic nerve injury [J] . Xin Li, Lumei Kang, Guilin Li, Molecular Pain . 2013,第1期

机译：鞘内瘦素抑制P2X2 / 3受体的表达并减轻慢性坐骨神经痛引起的神经性疼痛
3. Intrathecal leptin inhibits expression of the P2X_2/3 receptors and alleviates neuropathic pain induced by chronic constriction sciatic nerve injury [J] . Xin Li, Lumei Kang, Guilin Li, Molecular pain . 2013,第3期

机译：鞘内瘦素抑制P2X _{2/3 受体的表达并减轻慢性坐骨神经痛引起的神经性疼痛}
4. Involvement of Phosphorylated Extracellular Signal-Regulated Kinase in Facial Neuropathic Pain Following Cervical Nerve Injury in Rats [C] . Kobayashi, A, Imamura, International Congress on Neuropathic Pain . 2010

机译：大鼠宫颈神经损伤后面部神经性疼痛中磷酸化细胞外信号调节激酶的参与
5. Maladaptive synaptogenesis induced by interaction of voltage gated calcium channel subunit alpha2delta-1 and thrombospondin-4 represents a new mechanism underlying neuropathic pain processing in nerve injury models. [D] . Yu, Peter Yanhui. 2016

机译：电压门控钙通道亚基α2delta-1和血小板反应蛋白-4相互作用引起的适应性突触形成是神经损伤模型中神经性疼痛处理的新机制。
6. Intrathecal leptin inhibits expression of the P2X2/3 receptors and alleviates neuropathic pain induced by chronic constriction sciatic nerve injury [O] . Xin Li, Lumei Kang, Guilin Li, 2013

机译：鞘内瘦素抑制P2X2 / 3受体的表达并减轻慢性坐骨神经痛引起的神经性疼痛
7. Effect of delayed intrathecal administration of capsaicin on neuropathic pain induced by chronic constriction injury of the sciatic nerve in rats [O] . Maxim Eckmann, Kun Zhang, Thomas Prihoda, 2014

机译：胃肠酸血清血清抑制对大鼠坐骨神经慢性收缩损伤致神经性疼痛的影响

Effect of delayed intrathecal administration of capsaicin on neuropathic pain induced by chronic constriction injury of the sciatic nerve in rats

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