HCG (1500IU) administration on day 3 after oocytes retrieval following GnRH-agonist trigger for final follicular maturation results in high sufficient mid luteal progesterone levels - a proof of concept

摘要

BackgroundControlled ovarian hyperstimulation (COH) which combining GnRH antagonist co-treatment and GnRH agonist trigger with an additional 1500 IU hCG luteal rescue on day of oocytes retrieval, has become a common tool aiming to reduce severe ovarian hyperstimulation syndrome (OHSS). In the present, proof of concept study, we evaluate whether by deferring the hCG rescue bolus for 3 days, we are still able to rescue the luteal phase.