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Synthesis and Biological Evaluation of New Hydrazone Derivatives of Quinoline and Their Cu(II) and Zn(II) Complexes against Mycobacterium tuberculosis

机译：喹啉新型Hy衍生物及其对结核分枝杆菌的Cu（Ⅱ）和Zn（Ⅱ）配合物的合成及生物学评价

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摘要

A new series of quinoline hydrazone derivatives and their metal complexes have been synthesized and their biological properties have been evaluated against Mycobacterium tuberculosis (H37 RV strain). Most of the newly synthesized compounds displayed 100% inhibitory activity at a concentration of 6.25–25 μg/mL, against Mycobacterium tuberculosis. Fluorescence properties of all the synthesized compounds have been studied.

机译：合成了一系列新的喹line衍生物及其金属配合物，并评估了其对结核分枝杆菌（H37 RV菌株）的生物学特性。大多数新合成的化合物在6.25–25μg / mL的浓度下对结核分枝杆菌均表现出100％的抑制活性。已经研究了所有合成化合物的荧光性质。

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期刊名称 Bioinorganic Chemistry and Applications
作者
Mustapha C. Mandewale; Bapu Thorat; Dnyaneshwar Shelke; Ramesh Yamgar;
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作者单位

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年(卷),期 2015(2015),-1
年度 2015
页码 153015
总页数 14
原文格式 PDF
正文语种
中图分类分子生物学;
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专利

1. Synthesis and Biological Evaluation of New Hydrazone Derivatives of Quinoline and Their Cu(II) and Zn(II) Complexes against Mycobacterium tuberculosis [J] . Mandewale Mustapha C., Thorat Bapu, Shelke Dnyaneshwar, Bioinorganic chemistry and applications . 2015,第Null期

机译：喹啉新型Hy衍生物及其对结核分枝杆菌的Cu（II）和Zn（II）配合物的合成及生物学评价
2. Synthesis and Biological Evaluation of New Hydrazone Derivatives of Quinoline and Their Cu(II) and Zn(II) Complexes againstMycobacterium tuberculosis [J] . Mustapha C.Mandewale, BapuThorat, DnyaneshwarShelke, Bioinorganic chemistry and applications . 2015,第7期

机译：喹啉新型Hy衍生物及其对结核分枝杆菌的Cu（Ⅱ）和Zn（Ⅱ）配合物的合成及生物学评价
3. Synthesis, Characterization and Biological Activities of Cu(II), Co(II), Mn(II), Fe(II), and UO2(VI) Complexes with a New Schiff Base Hydrazone: O-Hydroxyacetophenone-7-chloro-4-quinoline Hydrazone [J] . Nora H. Al-Shaalan Molecules . 2011,第10期

机译：具有新型席夫碱Hy的Cu（II），Co（II），Mn（II），Fe（II）和UO2（VI）配合物的合成，表征和生物活性：O-羟基乙酰苯酮-7-chloro-4-喹啉Hy
4. Synthesis, Characterization and Biological Activity Evaluation of Novel Pd(II) and Pt(II) Complexes with Heterocyclic Hydrazone Ligands [C] . N. R. Filipovic, T. R. Todorovic, D. M. Sladic, Yugoslav Materials Restarch Society Conference . 2007

机译：用杂环腙配体的新型Pd（II）和Pt（II）配合物的合成，表征和生物活性评价
5. Cu (II) Catalyzed Gateways In The Synthesis of Acridine Derivatives and Their Biological Evaluation as Anti-Cancer Drugs [D] . Komati, Rajesh 2014

机译：铜（II）催化的Gateway啶衍生物合成途径及其作为抗癌药物的生物学评价
6. Synthesis Characterization and Biological Activities of Cu(II) Co(II) Mn(II) Fe(II) and UO2(VI) Complexes with a New Schiff Base Hydrazone: O-Hydroxyacetophenone-7-chloro-4-quinoline Hydrazone [O] . Nora H. Al-Shaalan 2011

机译：具有新型席夫碱Hy的Cu（II）Co（II）Mn（II）Fe（II）和UO2（VI）配合物的合成表征和生物活性：O-羟基乙酰苯酮-7-chloro-4-喹Hy Hy
7. Synthesis, structural studies and antituberculosis evaluation of new hydrazone derivatives of quinoline and their Zn(II) complexes [O] . Mandewale Mustapha C., Thorat Bapu, Nivid Y., 2016

机译：喹啉新衍生物及其Zn（II）配合物的合成，结构研究和抗结核评价

Synthesis and Biological Evaluation of New Hydrazone Derivatives of Quinoline and Their Cu(II) and Zn(II) Complexes against Mycobacterium tuberculosis

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