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True color scanning laser ophthalmoscopy and optical coherence tomography handheld probe

机译:真彩色扫描激光检眼镜和光学相干断层扫描手持式探头

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摘要

Scanning laser ophthalmoscopes (SLOs) are able to achieve superior contrast and axial sectioning capability compared to fundus photography. However, SLOs typically use monochromatic illumination and are thus unable to extract color information of the retina. Previous color SLO imaging techniques utilized multiple lasers or narrow band sources for illumination, which allowed for multiple color but not “true color” imaging as done in fundus photography. We describe the first “true color” SLO, handheld color SLO, and combined color SLO integrated with a spectral domain optical coherence tomography (OCT) system. To achieve accurate color imaging, the SLO was calibrated with a color test target and utilized an achromatizing lens when imaging the retina to correct for the eye’s longitudinal chromatic aberration. Color SLO and OCT images from volunteers were then acquired simultaneously with a combined power under the ANSI limit. Images from this system were then compared with those from commercially available SLOs featuring multiple narrow-band color imaging.
机译:与眼底摄影相比,扫描激光检眼镜(SLO)能够实现出色的对比度和轴向切片能力。但是,SLO通常使用单色照明,因此无法提取视网膜的颜色信息。以前的彩色SLO成像技术利用多个激光器或窄带光源进行照明,从而可以进行多种颜色成像,但不能像眼底照相那样进行“真彩色”成像。我们描述了第一个“真彩色” SLO,手持式彩色SLO和与光谱域光学相干断层扫描(OCT)系统集成的组合式彩色SLO。为了实现准确的彩色成像,对SLO进行了色彩测试目标校准,并在对视网膜成像时使用消色差透镜来校正眼睛的纵向色差。然后,在ANSI限制下,以组合功率同时从志愿者那里获取彩色SLO和OCT图像。然后将来自该系统的图像与来自具有多个窄带彩色成像功能的市售SLO的图像进行比较。

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