首页> 美国卫生研究院文献>Biomedical Optics Express >Flexible transbronchial optical frequency domain imaging smart needle for biopsy guidance
【2h】

Flexible transbronchial optical frequency domain imaging smart needle for biopsy guidance

机译:柔性经支气管光学频域成像智能针用于活检指导

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

Transbronchial needle aspiration (TBNA) is a procedure routinely performed to diagnose peripheral pulmonary lesions. However, TBNA is associated with a low diagnostic yield due to inappropriate needle placement. We have developed a flexible transbronchial optical frequency domain imaging (TB-OFDI) catheter that functions as a “smart needle” to confirm the needle placement within the target lesion prior to biopsy. The TB-OFDI smart needle consists of a flexible and removable OFDI catheter (430 µm dia.) that operates within a standard 21-gauge TBNA needle. The OFDI imaging core is based on an angle polished ball lens design with a working distance of 160 µm from the catheter sheath and a spot size of 25 µm. To demonstrate the potential of the TB-OFDI smart needle for transbronchial imaging, an inflated excised swine lung was imaged through a standard bronchoscope. Cross-sectional and longitudinal OFDI results reveal the detailed network of alveoli in the lung parenchyma suggesting that the TB-OFDI smart needle may be a useful tool for guiding biopsy acquisition to increase the diagnostic yield.
机译:经支气管针吸(TBNA)是一种常规程序,用于诊断周围性肺部病变。但是,由于针头放置不当,TBNA诊断率低。我们已经开发了一种灵活的经支气管光学频域成像(TB-OFDI)导管,可作为“智能针头”在活检前确认针头在目标病变内的位置。 TB-OFDI智能针头由可移动的OFDI导管(直径430 µm)组成,可在标准21号TBNA针头内操作。 OFDI成像核心基于角抛光球透镜设计,距导管鞘的工作距离为160 µm,光斑尺寸为25 µm。为了证明TB-OFDI智能针头在经支气管成像中的潜力,通过标准支气管镜对膨胀的切除的猪肺成像。 OFDI的横截面和纵向结果揭示了肺实质中的肺泡的详细网络,表明TB-OFDI智能针可能是指导活检采集以提高诊断率的有用工具。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号