American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia

摘要

Background:Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction mediated by platelet-activating antibodies that target complexes of platelet factor 4 and heparin. Patients are at markedly increased risk of thromboembolism.