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Expression of the costimulatory molecule B7-H3 is associated with prolonged survival in human pancreatic cancer

机译：共刺激分子B7-H3的表达与人类胰腺癌的长期生存有关

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BackgroundCostimulatory signaling has been implicated as a potential regulator of antitumor immunity in various human cancers. In contrast to the negative prognostic value of aberrant B7-H1 expression by pancreatic cancer cells, the role of B7-H3 is still unknown. Therefore, we investigated the expression pattern and clinical significance of B7-H3 expression in human pancreatic cancer.

机译：背景技术共刺激信号传导已被暗示为各种人类癌症中抗肿瘤免疫力的潜在调节剂。与胰腺癌细胞异常表达B7-H1的阴性预后相反，B7-H3的作用仍是未知的。因此，我们研究了B7-H3在人胰腺癌中的表达模式及其临床意义。

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期刊名称 BMC Cancer
作者
Martin Loos; Dennis M Hedderich; Malte Ottenhausen; Nathalia A Giese; Melanie Laschinger; Irene Esposito; Jörg Kleeff; Helmut Friess;
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作者单位

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年(卷),期 2009(9),-1
年度 2009
页码 463
总页数 10
原文格式 PDF
正文语种
中图分类肿瘤学;
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1. The coexpression and clinical significance of costimulatory molecules B7-H1, B7-H3, and B7-H4 in human pancreatic cancer [J] . Yan Chen, Jing Sun, Hua Zhao, OncoTargets and therapy . 2014,第3期

机译：共刺激分子B7-H1，B7-H3和B7-H4在人类胰腺癌中的共表达及其临床意义
2. Prolonged survival in pancreatic cancer patients with increased regucalcin gene expression: Overexpression of regucalcin suppresses the proliferation in human pancreatic cancer MIA PaCa-2 cells in vitro [J] . Masayoshi Yamaguchi, Satoru Osuka, M. Neale Weitzmann, International journal of oncology . 2016,第5期

机译：调节性降钙素基因表达增加的胰腺癌患者的延长生存期：调节性降钙素的过量表达抑制人胰腺癌MIA PaCa-2细胞的体外增殖
3. Expression of costimulatory molecule B7-H3 and its prognostic implications in human acute leukemia [J] . Yixin Hu, Xin Lv, Yujie Wu, Hematology. . 2015,第4期

机译：共刺激分子B7-H3的表达及其在人类急性白血病中的预后意义
4. A Novel Small-Molecule IAP Antagonist, AZD5582, Draws Mcl-1 Down-Regulation for Induction of Apoptosis Through Targeting of cIAP1 and XIAP in Human Pancreatic Cancer [C] . Ih-Yeon Hwang, Seul Lee, Jai-Hee Moon, International Molecular Medicine Tri-Conference. . 2016

机译：一种新型的小分子IAP拮抗剂AZD5582，通过靶向CIAP1和XIAP在人胰腺癌中诱导诱导细胞凋亡的MCL-1下调
5. Constitutive expression of costimulatory ligands in tumor antigen-specific human T lymphocytes - A study investigating the therapeutic potential of auto- and transcostimulation in cancer immunotherapy [D] . Stephan, Matthias 2008

机译：共刺激配体在肿瘤抗原特异性人类T淋巴细胞中的组成性表达-研究自动和转共刺激在癌症免疫治疗中的治疗潜力的研究
6. The coexpression and clinical significance of costimulatory molecules B7-H1 B7-H3 and B7-H4 in human pancreatic cancer [O] . Yan Chen, Jing Sun, Hua Zhao, 2014

机译：共刺激分子B7-H1B7-H3和B7-H4在人类胰腺癌中的共表达及其临床意义
7. Expression of the costimulatory molecule B7-H3 is associated with prolonged survival in human pancreatic cancer [O] . 2009

机译：共刺激分子B7-H3的表达与人类胰腺癌的长期生存有关

Expression of the costimulatory molecule B7-H3 is associated with prolonged survival in human pancreatic cancer

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