Efficacy of 99mTc-DTPA SPECT/CT in diagnosing Orbitopathy in graves’ disease

摘要

BackgroundThe most frequently used methods of assessing Graves’ orbithopathy (GO) include: Clinical Activity Score (CAS), ultrasonography (USG), computed tomography (CT), and magnetic resonance imaging (MRI). There exists another, slightly forgotten, imaging method: single-photon emission computed tomography (SPECT) with the use of diethylenetriaminepentaacetic acid tagged with ^99mTc (^99mTc-DTPA). These days it is possible to conduct a SPECT examination fused with a CT scan (SPECT/CT), which increases the diagnostic value of the investigation. The aim of this paper is to evaluate the usefulness of ^99mTc-DTPA SPECT/CT in diagnosing Graves orbitopathy, as compared with other methods.