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The endocrine stress response is linked to one specific locus on chromosome 3 in a mouse model based on extremes in trait anxiety

机译：根据特质焦虑的极端情况内分泌应激反应与小鼠模型中3号染色体上的一个特定基因座相关

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BackgroundThe hypothalamic-pituitary-adrenal (HPA) axis is essential to control physiological stress responses in mammals. Its dysfunction is related to several mental disorders, including anxiety and depression. The aim of this study was to identify genetic loci underlying the endocrine regulation of the HPA axis.

机译：背景下丘脑-垂体-肾上腺（HPA）轴对于控制哺乳动物的生理应激反应至关重要。其功能障碍与多种精神障碍有关，包括焦虑和抑郁。这项研究的目的是确定HPA轴的内分泌调节的遗传基因座。

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期刊名称 BMC Genomics
作者
Mariya Gonik; Elisabeth Frank; Melanie S Keßler; Darina Czamara; Mirjam Bunck; Yi-Chun Yen; Benno Pütz; Florian Holsboer; Thomas Bettecken; Rainer Landgraf; Bertram Müller-Myhsok; Chadi Touma; Ludwig Czibere;
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作者单位

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年(卷),期 2012(13),-1
年度 2012
页码 579
总页数 15
原文格式 PDF
正文语种
中图分类遗传学;应用微生物学;
关键词
F2 Corticosterone Stress response HPA axis QTL;

机译：F2;皮质酮;应激反应;HPA轴;QTL;

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专利

1. The endocrine stress response is linked to one specific locus on chromosome 3 in a mouse model based on extremes in trait anxiety [J] . Mariya Gonik, Elisabeth Frank, Melanie S Ke?ler, BMC Genomics . 2012,第1期

机译：根据特质焦虑的极端情况，内分泌应激反应与小鼠模型中3号染色体上的一个特定基因座相关
2. Real-time imaging of amygdalar network dynamics in vitro reveals a neurophysiological link to behavior in a mouse model of extremes in trait anxiety [J] . AvrabosC., SotnikovS.V., DineJ., The Journal of Neuroscience: The Official Journal of the Society for Neuroscience . 2013,第41期

机译：体外杏仁核网络动力学的实时成像揭示了特质焦虑极端小鼠模型中行为的神经生理联系
3. A quantitative trait locus (LSq-1) on mouse chromosome 7 is linked to the absence of tissue loss after surgical hindlimb ischemia. [J] . Dokun AO, Keum S, Hazarika S, Circulation: An Official Journal of the American Heart Association . 2008,第9期

机译：小鼠第7号染色体上的数量性状基因座（LSq-1）与手术后肢缺血后组织丢失的缺乏相关。
4. Biomarker discovery by stable isotope labeling and quantitative mass spectrometry in a trait anxiety mouse model [C] . Christian Webhofer, Birgit Bisle, Katrin Haegler, ASMS Conference on Mass Spectrometry and Allied Topics . 2008

机译：稳定同位素标记和定量质谱中的生物标志物在特质焦虑小鼠模型中发现
5. Escape from X chromosome inactivation is an intrinsic property of the mouse Jarid1c locus. [D] . Li, Nan. 2009

机译：逃避X染色体失活是小鼠Jarid1c基因座的固有特性。
6. Real-Time Imaging of Amygdalar Network Dynamics In Vitro Reveals a Neurophysiological Link to Behavior in a Mouse Model of Extremes in Trait Anxiety [O] . Charilaos Avrabos, Sergey V. Sotnikov, Julien Dine, 2013

机译：体外的Amygdalar网络动态的实时成像显示出在特质焦虑的极端小鼠模型中的神经生理学联系
7. The endocrine stress response is linked to one specific locus on chromosome 3 in a mouse model based on extremes in trait anxiety [O] . Mariya Gonik, Elisabeth Frank, Melanie S Keßler, 2012

机译：内分泌应激反应与基于特质焦虑极端情况的小鼠模型中第3号染色体上的一个特定基因座相关
8. Qualitative Analysis of Mouse Specific-Locus Mutations: Information on Genetic Organization, Gene Expression, and the Chromosomal Nature of Induced Lesions [R] . Russell, L. B. 1982

机译：小鼠特异性基因座突变的定性分析：诱导损伤的遗传组织，基因表达和染色体性质的信息

The endocrine stress response is linked to one specific locus on chromosome 3 in a mouse model based on extremes in trait anxiety

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