Intensified hand-hygiene campaign including soap-and-water wash may prevent acute infections in office workers as shown by a recognized-exposure -adjusted analysis of a randomized trial

摘要

BackgroundVariable exposure to causative agents of acute respiratory (RTI) or gastrointestinal tract infections (GTI) is a significant confounding factor in the analysis of the efficacy of interventions concerning these infections. We had an exceptional opportunity to reanalyze a previously published dataset from a trial assessing the effect of enhanced hand hygiene on the occurrence of RTI or GTI in adults, after adjustment for reported exposure and other covariates.