Impact of physical exercises on immune function bone mineral density and quality of life in people living with HIV/AIDS: a systematic review with meta-analysis

摘要

BackgroundCompromised immune function, associated with human immune deficiency virus(HIV) infection, is improved by antiretroviral therapy(ART) which also decreases bone mineral density(BMD), and possibly the quality of life(QoL). However, physical(aerobic/resistance) exercises, were reported to induce reverse effects in uninfected individuals and were appraised in the literature for evidence of similar benefits in people living with HIV/AIDS(PLWHA). The main study objective was to evaluate the impact of physical (aerobic and resistance) exercises on CD⁴⁺ count, BMD and QoL in PLWHA.