How effective is tetracaine 4 gel before a peripherally inserted central catheter in reducing procedural pain in infants: a randomized double-blind placebo controlled trial ISRCTN75884221

摘要

BackgroundProcedural pain relief is sub-optimal in infants, especially small and vulnerable ones. Tetracaine gel 4% (Ametop^®, Smith-Nephew) provides pain relief in children and larger infants, but its efficacy in smaller infants and for peripherally inserted central catheters (PICC) remains uncertain. The objective of this trial was to assess the safety and efficacy of tetracaine gel on the pain response of very low birth weight (VLBW) infants during insertion of a PICC.