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pH-mediated upregulation of AQP1 gene expression through the Spi-B transcription factor

机译：pH值通过Spi-B转录因子上调AQP1基因表达

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摘要

BackgroundBicarbonate-based peritoneal dialysis (PD) fluids enhance the migratory capacity and damage-repair ability of human peritoneal mesothelial cells by upregulating AQP1. However, little is known about the underlying molecular mechanisms.

机译：背景基于碳酸氢盐的腹膜透析（PD）液通过上调AQP1增强人腹膜间皮细胞的迁移能力和损伤修复能力。然而，对潜在的分子机制知之甚少。

著录项

期刊名称 BMC Molecular Biology
作者
Yihui Zhai; Hong Xu; Qian Shen; Franz Schaefer; Claus P. Schmitt; Jing Chen; Haimei Liu; Jialu Liu; Jiaojiao Liu;
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作者单位

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年(卷),期 2018(19),-1
年度 2018
页码 4
总页数 9
原文格式 PDF
正文语种
中图分类分子生物学;
关键词
Aquaporin 1 pH Promoter Transcription Peritoneal dialysis fluids;

机译：水通道蛋白1;pH;促进剂;转录;腹膜透析液;

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专利

1. Isolation and characterization of Aquaporin 1 (AQP1), sodium/potassium-transporting ATPase subunit alpha-1 (Na/K-ATPase alpha 1), Heat Shock Protein 90 (HSP90), Heat Shock Cognate 71 (HSC71), Osmotic Stress Transcription Factor 1 (OSTF1) and Transcription Factor II B (TFIIB) genes from a euryhaline fish, Etroplus suratensis [J] . Sebastian Wilson, Sukumaran Sandhya, Zacharia P. U., Molecular biology reports . 2018,第6期

机译：水素1（AQP1），钠/钾传输ATP酶亚基α-1（Na / K-ATP酶α1），热休克蛋白90（HSP90），热休克同源71（HSC71），渗透应激转录因子的分离和表征来自euryhaline鱼的1（OSTF1）和转录因子II B（TFIIB）基因，etroplus suratensis
2. Desmin enters the nucleus of cardiac stem cells and modulates Nkx2.5 expression by participating in transcription factor complexes that interact with the nkx2.5 gene Desmin enters the nucleus of cardiac stem cells and modulates Nkx2.5 expression by participating in transcription factor complexes that interact with the nkx2.5 gene Desmin enters the nucleus of cardiac stem cells and modulates Nkx2.5 expression by participating in transcription factor complexes that interact with the nkx2.5 gene [J] . Sonja Gawlas, Yassemi Capetanaki, Christiane Fuchs, Biology Open . 2016,第2期

机译：Desmin进入心脏干细胞核并通过参与与nkx2.5基因相互作用的转录因子复合物调节Nkx2.5表达Desmin进入心脏干细胞的核并通过参与相互作用的转录因子复合物调节Nkx2.5表达与nkx2.5基因结合的Desmin通过参与与nkx2.5基因相互作用的转录因子复合物进入心脏干细胞核并调节Nkx2.5表达
3. Desmin enters the nucleus of cardiac stem cells and modulates Nkx2.5 expression by participating in transcription factor complexes that interact with the nkx2.5 gene Desmin enters the nucleus of cardiac stem cells and modulates Nkx2.5 expression by participating in transcription factor complexes that interact with the nkx2.5 gene Desmin enters the nucleus of cardiac stem cells and modulates Nkx2.5 expression by participating in transcription factor complexes that interact with the nkx2.5 gene [J] . Sonja Gawlas, Yassemi Capetanaki, Christiane Fuchs, Biology Open . 2016,第2期

机译：Desmin进入心脏干细胞核并通过参与与nkx2.5基因相互作用的转录因子复合物调节Nkx2.5表达Desmin进入心脏干细胞的核并通过参与相互作用的转录因子复合物调节Nkx2.5表达与nkx2.5基因结合的Desmin通过参与与nkx2.5基因相互作用的转录因子复合物进入心脏干细胞核并调节Nkx2.5表达
4. Cloud-Accelerated Data-Mining for Putative Heteromeric Transcription Factors and Target Genes Using Microarray Gene Expression Profiles [C] . Edward A. Salinas, Amitava Karmaker International Conference on Bioinformatics and Computational Biology . 2013

机译：使用微阵列基因表达谱的推定异致转录因子和靶基因的云加速数据挖掘
5. Positive and negative regulation of neuroendocrine gene expression by zinc finger transcription factors: Identification of a negative retinoic acid response element in the rat oxytocin promoter, and the cloning of a novel factor binding a conserved element critical for effective expression of the growth hormone gene [D] . Lipkin, Steven Monroe 1993

机译：锌指转录因子对神经内分泌基因表达的正向和负向调节：鉴定大鼠催产素启动子中的视黄酸阴性反应元件，并克隆与保守元件结合的新型因子，该元件对于生长激素基因的有效表达至关重要
6. Adipocyte expression of PU.1 transcription factor causes insulin resistance through upregulation of inflammatory cytokine gene expression and ROS production [O] . Ligen Lin, Weijun Pang, Keyun Chen, -1

机译：PU.1转录因子的脂肪细胞表达通过上调炎症细胞因子基因表达和ROS产生而引起胰岛素抵抗
7. pH-mediated upregulation of AQP1 gene expression through the Spi-B transcription factor [O] . Yihui Zhai, Hong Xu, Qian Shen, 2018

机译：通过SPI-B转录因子介导的AQP1基因表达的介导的Upregulation

pH-mediated upregulation of AQP1 gene expression through the Spi-B transcription factor

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