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Long-term outcome following additional rhBMP-7 application in revision surgery of aseptic humeral femoral and tibial shaft nonunion

机译：在无菌肱骨股骨和胫骨干骨不连的翻修手术中额外应用rhBMP-7后的长期结果

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摘要

BackgroundSurgical revision concepts for the treatment of aseptic humeral, femoral, and tibial diaphyseal nonunion were evaluated. It was analyzed if the range of time to bone healing was shorter, and if clinical and radiological long-term outcome was better following application of additional recombinant human Bone Morphogenetic Protein-7 (rhBMP-7) compared to no additional rhBMP-7 use.

机译：背景技术评估了无菌肱骨，股骨和胫骨干骨不连的外科手术修订概念。与不使用rhBMP-7相比，分析了使用额外的重组人骨形态发生蛋白7（rhBMP-7）后骨骼愈合的时间范围是否较短，以及临床和放射学的长期结果是否更好。

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期刊名称 BMC Musculoskeletal Disorders
作者
Simon Hackl; Christian Hierholzer; Jan Friederichs; Alexander Woltmann; Volker Bühren; Christian von Rüden;
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作者单位

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年(卷),期 2017(18),-1
年度 2017
页码 342
总页数 10
原文格式 PDF
正文语种
中图分类矫形学;免疫性疾病;
关键词
Nonunion Humerus Femur Tibia Recombinant human bone morphogenetic protein-7 (rhBMP-7) Bone graft Follow-up DASH LEFS SF-12;

机译：骨不连;肱骨;股骨;胫骨;重组人骨形态发生蛋白7（rhBMP-7）;骨移植;随访;DASH;LEFS;SF-12;

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专利

1. Long-term outcome following additional rhBMP-7 application in revision surgery of aseptic humeral, femoral, and tibial shaft nonunion [J] . Simon Hackl, Christian Hierholzer, Jan Friederichs, BMC Musculoskeletal Disorders . 2017,第1期

机译：在无菌肱骨，股骨和胫骨干骨不连的翻修手术中额外应用rhBMP-7进行长期治疗
2. Revision surgery for femoral shaft aseptic nonunion associated with broken distal locked screws [J] . Chia Wei Yu, Chi Chuan Wu Formosan journal of musculoskeletal disorders. . 2011,第1期

机译：股骨干无菌性骨不连伴远端锁定螺钉断裂的翻修手术
3. Efficacy and Safety of Long-Term Intravenous Tranexamic Acid Administration for Blood Management in Revision Surgery for Femoral Shaft Nonunion: A Retrospective Case-Control Study [J] . Zhimeng Wang, Yao Lu, Qiang Huang, Clinical and applied thrombosis/hemostasis : . 2021,第a期

机译：长期静脉内促进育种血液管理血液管理的疗效和安全性股骨轴不连锁术：回顾性案例对照研究
4. Fracture toughness of the femoral neck, femoral shaft, and tibial shaft in aged bone [C] . Christopher U.Brown, Yener N.Yeni, Timothy L.Norman ASME international mechanical engineering congress and exposition;IMECE . 1998

机译：老年骨中股骨颈，股骨干和胫骨干的断裂韧性
5. Demographics, Mechanism of Injury, Injury Severity, and Associated Injury Profiles of Patients with Femoral and Tibial Shaft Fractures: A Study of the National Trauma Databank [D] . Anandasivam, Nidharshan 2019

机译：人口统计学，损伤机制，伤病严重程度和股骨胫骨骨折患者的伤害谱：全国创伤数据库的研究
6. Efficacy and Safety of Long-Term Intravenous Tranexamic Acid Administration for Blood Management in Revision Surgery for Femoral Shaft Nonunion: A Retrospective Case-Control Study [O] . Zhimeng Wang, Yao Lu, Qiang Huang, 2021

机译：长期静脉静脉蛋白酸施氮疗法对股骨轴不连续血液管理的疗效和安全性：回顾性案例控制研究
7. Long-term outcome following additional rhBMP-7 application in revision surgery of aseptic humeral, femoral, and tibial shaft nonunion [O] . Hackl, Simon, Hierholzer, Christian, Friederichs, Jan, 2017

机译：在无菌肱骨，股骨和胫骨干骨不连的翻修手术中额外应用rhBMP-7后的长期结果

Long-term outcome following additional rhBMP-7 application in revision surgery of aseptic humeral femoral and tibial shaft nonunion

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