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Rosiglitazone infusion therapy following minimally invasive surgery for intracerebral hemorrhage evacuation decreases matrix metalloproteinase-9 and blood–brain barrier disruption in rabbits

机译：罗格列酮输注疗法在微创外科手术后用于脑内出血清除减少兔子的基质金属蛋白酶9和血脑屏障破坏

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摘要

BackgroundThe objective of this study was to investigate the effects of Rosiglitazone (RSG) infusion therapy following minimally invasive surgery (MIS) for intracerebral hemorrhage(ICH) evacuation on perihematomal secondary brain damage as assessed by MMP-9 levels, blood–brain barrier (BBB) permeability and neurological function.

机译：背景本研究的目的是研究罗非格列酮（RSG）输注疗法在微创手术（MIS）撤离脑出血（ICH）后对血肿性继发性脑损伤的作用，如MMP-9水平，血脑屏障（BBB））通透性和神经功能。

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期刊名称 BMC Neurology
作者
Guofeng Wu; Junjie Wu; Yu Jiao; Likun Wang; Fan Wang; Yingjun Zhang;
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作者单位

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年(卷),期 2015(15),-1
年度 2015
页码 37
总页数 8
原文格式 PDF
正文语种
中图分类神经病学;
关键词
Intracerebral hemorrhage Minimally invasive surgery Rosiglitazone PPARγ MMP-9 Blood–brain barrier;

机译：脑出血;微创手术;罗格列酮;PPARγ;MMP-9;血脑屏障;

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专利

1. Rosiglitazone infusion therapy following minimally invasive surgery for intracerebral hemorrhage evacuation decreases matrix metalloproteinase-9 and blood–brain barrier disruption in rabbits [J] . Guofeng Wu, Junjie Wu, Yu Jiao, BMC Neurology . 2015,第1期

机译：rosiglitazone输液治疗后脑出血疏散的微创手术下降降低了兔子的基质金属蛋白酶-9和血脑屏障中断
2. Rosiglitazone Infusion Therapy Following Minimally Invasive Surgery for Intracranial Hemorrhage Evacuation Decreased Perihematomal Glutamate Content and Blood-Brain Barrier Permeability in Rabbits [J] . Guofeng Wu, Yu Jiao, Junjie Wu, World neurosurgery . 2018,第期

机译：罗格列酮输注治疗后颅内出血疏散的微创手术下降降低了兔血症谷氨酸含量和血脑屏障渗透性
3. Minimally Invasive Procedures for Evacuation of Intracerebral Hemorrhage Reduces Perihematomal Glutamate Content, Blood–Brain Barrier Permeability and Brain Edema in Rabbits [J] . Guofeng Wu, Chang Li, Likun Wang, Neurocritical Care . 2011,第1期

机译：撤出脑出血的微创手术减少了兔的血肿周围谷氨酸含量，血脑屏障通透性和脑水肿
4. Detection of transient ischemia and hemorrhage in blood-brain barrier disruption by high-frequency ultrasound imaging [C] . Ting Chien-Yu, Fan Ching-Hsiang, Yeh Chih-Kuang 2010 IEEE International Ultrasonics Symposium . 2010

机译：高频超声成像检测血脑屏障破坏中的短暂性缺血和出血
5. Magnetic resonance imaging investigations of ischemic stroke, intracerebral hemorrhage and blood-brain barrier pathology. [D] . Karki, Kishor. 2009

机译：缺血性脑卒中，脑出血和血脑屏障病理的磁共振成像研究。
6. Minimally Invasive Surgery plus rt-PA for Intracerebral Hemorrhage Evacuation (MISTIE) Decreases Perihematomal Edema [O] . W. Andrew Mould, J. Ricardo Carhuapoma, John Muschelli, -1

机译：微创手术加上RT-PA用于脑内出血疏散（Mistie）降低炎性水肿
7. Rosiglitazone infusion therapy following minimally invasive surgery for intracerebral hemorrhage evacuation decreases matrix metalloproteinase-9 and blood–brain barrier disruption in rabbits [O] . Guofeng Wu, Junjie Wu, Yu Jiao, 2015

机译：罗格列酮输注疗法在微创外科手术后用于脑内出血清除减少了兔子体内的基质金属蛋白酶9和血脑屏障破坏

Rosiglitazone infusion therapy following minimally invasive surgery for intracerebral hemorrhage evacuation decreases matrix metalloproteinase-9 and blood–brain barrier disruption in rabbits

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