Pharmacological targeting of secondary brain damage following ischemic or hemorrhagic stroke traumatic brain injury and bacterial meningitis - a systematic review and meta-analysis

摘要

BackgroundThe effectiveness of pharmacological strategies exclusively targeting secondary brain damage (SBD) following ischemic stroke, aneurysmal subarachnoid hemorrhage, aSAH, intracerebral hemorrhage (ICH), traumatic brain injury (TBI) and bacterial meningitis is unclear. This meta-analysis studied the effect of SBD targeted treatment on clinical outcome across the pathological entities.