Effects of dexmedetomidine on TNF-α and interleukin-2 in serum of rats with severe craniocerebral injury

摘要

BackgroundDexmedetomidine is a highly selective adrenergic receptor agonist, which has a dose-dependent sedative hypnotic effect. Furthermore, it also has pharmacological properties, and the ability to inhibit sympathetic activity and improve cardiovascular stability during an operation. However, its protective effect on patients with severe craniocerebral injury in the perioperative period remains unclear.