Effectiveness of second-generation antipsychotics: a naturalistic randomized comparison of olanzapine quetiapine risperidone and ziprasidone

摘要

BackgroundNo clear recommendations exist regarding which antipsychotic drug should be prescribed first for a patient suffering from psychosis. The primary aims of this naturalistic study were to assess the head-to-head effectiveness of first-line second-generation antipsychotics with regards to time until drug discontinuation, duration of index admission, time until readmission, change of psychopathology scores and tolerability outcomes.