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Latent tuberculosis infection and associated risk factors among people living with HIV and apparently healthy blood donors at the University of Gondar referral hospital Northwest Ethiopia

机译:埃塞俄比亚西北部贡达尔大学转诊医院的艾滋病毒感染者和显然健康的献血者中潜在的肺结核感染及相关危险因素

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摘要

ObjectiveImmuno-compromised individuals with latent tuberculosis infection (LTBI) are at an increased risk for tuberculosis reactivation compared with the general population. The aim of this study was to determine the prevalence of latent tuberculosis infection among people living with human immunodeficiency virus (PLWH) and apparently healthy blood donors. Human Immunodeficiency Virus positive individuals and for the purpose of comparison apparently healthy blood donors were enrolled. Blood sample was collected and tested for LTBI using QuantiFeron-TB Gold In-Tube assay (QFT-GIT) and CD4+ T cell count was determined by using BD FACS count.
机译:目的与一般人群相比,患有潜伏性结核感染(LTBI)的免疫功能低下的人群再次发生结核病的风险更高。这项研究的目的是确定人免疫缺陷病毒(PLWH)患者和显然健康的献血者中潜伏性结核感染的患病率。招募了人类免疫缺陷病毒阳性个体,并且为了进行比较,目的是招募了健康的献血者。收集血样,并使用QuantiFeron-TB金管内分析(QFT-GIT)测试LTBI,并通过BD FACS计数确定CD4 + T细胞计数。

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