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Modification effect of fenofibrate therapy a longitudinal epigenomic-wide methylation study of triglycerides levels in the GOLDN study

机译：非诺贝特疗法的修饰作用一项在GOLDN研究中对甘油三酸酯水平进行纵向基因组学全甲基化研究

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BackgroundIdentification of interactions between epigenetic factors and treatments might lead to personalized intervention of diseases. This paper aims to examine the modification effect of fenofibrate therapy on the association of methylation levels and fasting blood triglycerides (TG), and the related biological pathways among methylation sites.

机译：背景识别表观遗传因素与治疗之间的相互作用可能会导致疾病的个性化干预。本文旨在探讨非诺贝特治疗对甲基化水平与空腹血液甘油三酸酯（TG）关联的修饰作用，以及甲基化位点之间的相关生物途径。

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期刊名称 BMC Genetics
作者
Runmin Wei; Yanyan Wu;
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作者单位

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年(卷),期 2018(19),Suppl 1
年度 2018
页码 75
总页数 6
原文格式 PDF
正文语种
中图分类遗传学;
关键词
Methylation TG Repeated measures Mixed models Interaction GSEA;

机译：甲基化;TG;重复测量;混合模型;相互作用;GSEA;

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专利

1. Modification effect of fenofibrate therapy, a longitudinal epigenomic-wide methylation study of triglycerides levels in the GOLDN study [J] . Runmin Wei, Yanyan Wu BMC Genetics . 2018,第1期

机译：非诺贝特疗法的修饰作用，一项在GOLDN研究中对甘油三酸酯水平进行纵向基因组学全甲基化研究
2. The PPAR alpha gene is associated with triglyceride, low-density cholesterol and inflammation marker response to fenofibrate intervention: The GOLDN study [J] . Frazier-WoodA.C., OrdovasJ.M., StrakaR.J., The pharmacogenomics journal . 2013,第4期

机译：PPARα基因与甘油三酸酯，低密度胆固醇和非诺贝特干预的炎症标志物反应有关：GOLDN研究
3. Lipid changes due to fenofibrate treatment are not associated with changes in DNA methylation patterns in the GOLDN study [J] . Mithun Das, M. Ryan Irvin, Jin Sha, Frontiers in Genetics . 2015,第4期

机译：非诺贝特治疗引起的脂质变化与GOLDN研究中DNA甲基化模式的变化无关
4. The Association between Prenatal Selenium-Related DNA Methylation Modifications in Placenta and Newborn Neurobehavioral Development: An Epigenome-Wide Study of Two U.S. Birth Cohorts [C] . Fu-Ying Tian, Todd M. Everson, Barry Lester, Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：胎盘中与硒相关的DNA甲基化修饰与新生儿神经行为发育之间的关联：两个美国出生队列的表观基因组研究
5. Examining the impact of student-level and school-level variables on the disproportionate representation of minority students in special education using data from the Early Childhood Longitudinal Study-Kindergarten cohort. [D] . Ruedel, Kristin L. A. 2008

机译：使用来自儿童早期纵向研究-幼儿园队列的数据，检验学生水平和学校水平变量对少数民族学生在特殊教育中比例过高的影响。
6. The PPAR Alpha gene is associated with triglyceride low-density cholesterol and inflammation marker response to fenofibrate intervention: The GOLDN Study [O] . A.C. Frazier-Wood, J.M Ordovas, R.J. Straka, -1

机译：PPARα基因与甘油三酯低密度胆固醇和对面包纤维干预的炎症结合有关：Goldn研究
7. Modification effect of fenofibrate therapy, a longitudinal epigenomic-wide methylation study of triglycerides levels in the GOLDN study [O] . Runmin Wei, Yanyan Wu 2018

机译：细胞纤维素治疗的改性效果，GOLDN研究中甘油三酯水平纵向外观甲基化研究

Modification effect of fenofibrate therapy a longitudinal epigenomic-wide methylation study of triglycerides levels in the GOLDN study

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