Can we Save the rectum by watchful waiting orTransAnal microsurgery following (chemo)Radiotherapy versus Total mesorectal excisionfor early REctal Cancer (STAR-TREC study)?:protocol for a multicentre randomised feasibility study

摘要

IntroductionTotal mesorectal excision (TME) is the highly effective standard treatment for rectal cancer but is associated with significant morbidity and may be overtreatment for low-risk cancers. This study is designed to determine the feasibility of international recruitment in a study comparing organ-saving approaches versus standard TME surgery.