首页>
美国卫生研究院文献>The Journal of Physiology
>Physiological evidence for a trans-basal ganglia pathway linking extrastriate visual cortex and the superior colliculus
【2h】
Physiological evidence for a trans-basal ganglia pathway linking extrastriate visual cortex and the superior colliculus
Non-technical summaryThe superior colliculus (SC) is a subcortical brain structure critically involved in the production of eye and head movements to novel or salient visual cues. But to accomplish its function, an input from visual cortex also is required. Because visual cortex projects directly to the SC, this route is typically viewed as the predominant way by which cortex exerts higher-level control over SC-mediated behaviours. However, anatomical studies suggest that other multi-neuronal circuits through the basal ganglia, a collection of interconnected structures involved in decision making, might provide an alternative way for cortex to influence the SC. The present study provides physiological evidence for such an alternative route and affords additional insights into how the brain initiates and controls movements in response to visual cues. Such knowledge could be important for developing therapies to lessen the effects of visual deficits in patients experiencing loss of function following head trauma or stroke.
展开▼