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Chemotherapy vs tamoxifen in platinum-resistant ovarian cancer: a phase III randomised multicentre trial (Ovaresist)

机译：铂抗性卵巢癌的化学疗法与他莫昔芬比较：III期随机多中心试验（Ovaresist）

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Background: Chemotherapy in platinum-resistant ovarian cancer (PROC) aims for palliation and prolonging of progression-free survival (PFS). This study compares Health-related Quality of Life (HRQoL) and efficacy between single-agent chemotherapy and tamoxifen in PROC.

机译：背景：对铂类耐药的卵巢癌（PROC）的化学疗法旨在缓解和延长无进展生存期（PFS）。这项研究比较了PROC中单药化疗和他莫昔芬之间健康相关的生活质量（HRQoL）和疗效。

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期刊名称 British Journal of Cancer
作者
Kristina Lindemann; Emma Gibbs; Elisabeth Åvall-Lundqvist; Rene dePont Christensen; Kathrine Woie; Marten Kalling; Annika Auranen; Seija Grenman; Thomas Hoegberg; Per Rosenberg; Tone Skeie-Jensen; Elisabet Hjerpe; Anne Dørum; Val Gebski; Gunnar Kristensen;
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年(卷),期 2017(116),4
年度 2017
页码 455–463
总页数 9
原文格式 PDF
正文语种
中图分类肿瘤学 ;
关键词
platinum-resistent ovarian cancer chemotherapy tamoxifen quality of life survival phase III;

机译：铂耐药卵巢癌;化学疗法;他莫昔芬;生活质量;生存期;III期;

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专利

1. Chemotherapy vs tamoxifen in platinum-resistant ovarian cancer: a phase III, randomised, multicentre trial (Ovaresist) [J] . KristinaLindemann, EmmaGibbs, Elisabeth?vall-Lundqvist, British Journal of Cancer . 2017 ,第4期

机译：铂抗性卵巢癌的化学疗法与他莫昔芬比较：III期随机，多中心试验（Ovaresist）
2. Berzosertib plus gemcitabine versus gemcitabine alone in platinum-resistant high-grade serous ovarian cancer: a multicentre, open-label, randomised, phase 2 trial [J] . The lancet oncology . 2020 ,第7期

机译：Berzosertib加上吉西他滨与吉西众滨独行在铂抗性高档浆液癌症中：多方形，开放标签，随机，第2期试验
3. Sorafenib plus topotecan versus placebo plus topotecan for platinum-resistant ovarian cancer (TRIAS): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial [J] . Radoslav Chekerov, Felix Hilpert, Sven Mahner, The lancet oncology . 2018 ,第9期

机译：Sorafenib Plus Topotecan Versus Alumbo Plus Topotecan为铂腐蚀卵巢癌（Trias）：多方形，随机，双盲，安慰剂控制，第2期试验
4. Clinical Outcome of Breast and Ovarian Cancer Patients Treated after High-Dose Chemotherapy and Autologous Stem Cell Rescue with Theratope (STn-KLH) Cancer Vaccine: Theratope (STn-KLH) Cancer Vaccine following Autologous Transplant [C] . Leona A. Holmberg, Katherine A. Guthrie, Brenda M. Sandmaier Chemical glycobiology . -1

机译：大剂量化学疗法和自体干细胞拯救治疗的Theratope（STn-KLH）癌症疫苗治疗的乳腺癌和卵巢癌患者的临床结果：自体移植后的Theratope（STn-KLH）癌症疫苗
5. Sexuality and gynaecological cancer: A randomised control trial to evaluate the effectiveness of a group psychoeducational intervention in improving the sexual health of women with gynaecological cancer treated with radiotherapy [D] . Jeffries, Sherryl Anne 2003

机译：性与妇科癌症：一项随机对照试验，旨在评估团体心理教育干预措施对经放射治疗的妇科癌症妇女改善性健康的有效性
6. PIPAC-OV3: A multicenter open-label randomized two-arm phase III trial of the effect on progression-free survival of cisplatin and doxorubicin as Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC) vs. chemotherapy alone in patients with platinum-resistant recurrent epithelial ovarian fallopian tube or primary peritoneal cancer [O] . Naoual Bakrin, Clemens Tempfer, Giovanni Scambia, 2018

机译：PIPAC-OV3：一项多中心开放标签随机三臂III期临床试验对加压铂-腹膜内气雾剂化疗（PIPAC）与单独化疗的铂-铂类患者对顺铂和阿霉素的无进展生存期有影响耐药的复发性上皮性卵巢癌输卵管癌或原发性腹膜癌
7. Chemotherapy vs tamoxifen in platinum-resistant ovarian cancer : A phase III, randomised, multicentre trial (Ovaresist) [O] . Lindemann, Kristina, Gibbs, Emma, Åvall Lundqvist, Elisabeth, 2017

机译：化疗与他莫昔芬治疗铂类耐药卵巢癌：一项III期，随机，多中心试验（Ovaresist）

Chemotherapy vs tamoxifen in platinum-resistant ovarian cancer: a phase III randomised multicentre trial (Ovaresist)

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