Discontinuation of proton pump inhibitors during assessment of chromogranin A levels in patients with neuroendocrine tumours

摘要

Background: The aim of this prospective study was to examine whether discontinuation of proton pump inhibitors (PPIs) or replacement by H2-receptor antagonists (H2RA) resulted in a decrease of chromogranin A (CgA) levels in 196 patients with well-differentiated neuroendocrine tumours (NETs).