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Phase II randomised trial of chemoradiotherapy with FOLFOX4 or cisplatin plus fluorouracil in oesophageal cancer

机译：FOLFOX4或顺铂加氟尿嘧啶放化疗治疗食管癌的II期随机试验

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Background: Concurrent chemoradiotherapy is a valuable treatment option for localised oesophageal cancer (EC), but improvement is still needed. A randomised phase II trial was initiated to assess the feasibility and efficacy in terms of the endoscopic complete response rate (ECRR) of radiotherapy with oxaliplatin, leucovorin and fluorouracil (FOLFOX4) or cisplatin/fluorouracil.

机译：背景：同时放化疗是局限性食管癌（EC）的一种有价值的治疗选择，但仍需要改进。开始一项随机的II期临床试验，以评估用奥沙利铂，亚叶酸钙和氟尿嘧啶（FOLFOX4）或顺铂/氟尿嘧啶放射治疗的内镜完全缓解率（ECRR）。

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期刊名称 British Journal of Cancer
作者
T Conroy; Y Yataghène; P L Etienne; P Michel; H Senellart; J L Raoul; L Mineur; M Rives; X Mirabel; B Lamezec; E Rio; E Le Prisé; D Peiffert; A Adenis;
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年(卷),期 2010(103),9
年度 2010
页码 1349–1355
总页数 7
原文格式 PDF
正文语种
中图分类肿瘤学 ;
关键词
oesophageal cancer chemoradiotherapy oxaliplatin;

机译：食道癌;放化疗;奥沙利铂;

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专利

1. 食管癌患者同期放化疗顺铂加氟尿嘧啶方案Ⅱ期临床试验 [J] . 蔺强, 高献书, 乔学英, 癌症（英文版） . 2008 ,第010期
2. Phase II randomised trial of chemoradiotherapy with FOLFOX4 or cisplatin plus fluorouracil in oesophageal cancer [J] . T Conroy, Y Yataghène, P L Etienne, British Journal of Cancer . 2010 ,第9期

机译：FOLFOX4或顺铂加氟尿嘧啶放化疗治疗食管癌的II期随机试验
3. Definitive chemoradiotherapy with FOLFOX versus fluorouracil and cisplatin in patients with oesophageal cancer (PRODIGE5/ACCORD17): Final results of a randomised, phase 2/3 trial [J] . ConroyT., GalaisM.-P., RaoulJ.-L., The lancet oncology . 2014 ,第3期

机译：食管癌患者使用FOLFOX对比氟尿嘧啶和顺铂进行明确的放化疗（PRODIGE5 / ACCORD17）：一项2/3期随机试验的最终结果
4. Cisplatin and 5-fluorouracil with or without epidermal growth factor receptor inhibition panitumumab for patients with non-resectable, advanced or metastatic oesophageal squamous cell cancer: a prospective, open-label, randomised phase III AIO/EORTC trial (POWER) [J] . Annals of oncology: official journal of the European Society for Medical Oncology . 2020 ,第2期

机译：具有或没有表皮生长因子受体抑制胰岛素的顺铂和5-氟尿嘧啶，用于患有不可切除的，晚期或转移性食管鳞癌癌症癌症的胰癌：一种预期，开放标签，随机阶段III AIO / EORTC试验（POWER）
5. Clinical studies of SP1049C, a polymer based anthracycline effective against drug resistant tumors. Results of phase II trial and pivotal phase Ⅲ program in upper gastrointestinal cancer indications [C] . Valery Alakhov Controlled Release Society Annual Meeting and Exposition . 2007

机译：SP1049C的临床研究，一种基于聚合物的蒽环类药物可有效抵抗耐药性肿瘤。上消化道癌适应症的II期试验和关键性III期试验结果
6. Sexuality and gynaecological cancer: A randomised control trial to evaluate the effectiveness of a group psychoeducational intervention in improving the sexual health of women with gynaecological cancer treated with radiotherapy [D] . Jeffries, Sherryl Anne 2003

机译：性与妇科癌症：一项随机对照试验，旨在评估团体心理教育干预措施对经放射治疗的妇科癌症妇女改善性健康的有效性
7. Chemoradiotherapy with concurrent gemcitabine and cisplatin with or without sequential chemotherapy with gemcitabine/cisplatin vs chemoradiotherapy with concurrent 5-fluorouracil in patients with locally advanced pancreatic cancer – a multi-centre randomised phase II study [O] . R Wilkowski, S Boeck, S Ostermaier, 2009

机译：局部晚期胰腺癌患者中同时进行吉西他滨和顺铂联合放化疗或不联合进行吉西他滨/顺铂化疗与同期5-氟尿嘧啶放化疗联合5-氟尿嘧啶治疗
8. Phase II randomised trial of chemoradiotherapy with FOLFOX4 or cisplatin plus fluorouracil in oesophageal cancer [O] . Conroy, Thierry, Yataghène, Y., Etienne, P.-L., 2010

机译：FOLFOX4或顺铂加氟尿嘧啶放化疗治疗食管癌的II期随机试验

Phase II randomised trial of chemoradiotherapy with FOLFOX4 or cisplatin plus fluorouracil in oesophageal cancer

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