AIM—To assess uniformity of the corneal endothelial cell mosaic in children. METHODS—36 healthy children (5-11 years old, 16 boys, 20 girls) were assessed by specular microscopy. Endothelial cell density (ECD) was calculated from measured cell areas, and the number of sides/cell noted. RESULTS—Average values for ECD and cell areas were 3987 cells/mm2 (95% CI 3806 to 4168 cells/mm2) and 278 (SD 85) µm2 respectively, with normal distribution (COV 28.2%, range 17.4to 39.2%) and with the average percentage of six sided cells being 66.6% (8.8%). Cell area was positively correlated to number of cell sides (p <0.01, r2=0.993), but the percentage of six sided cells was negatively correlated to ECD (p <0.01, r=0.493). CONCLUSION—A high ECD occurs in children, but this does not mean there is a high percentage of "hexagons".
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机译：目的：评估儿童角膜内皮细胞镶嵌的均匀性。 方法：对36例健康儿童（5-11岁，男16例，女20例）进行了镜检。根据测得的细胞面积计算内皮细胞密度（ECD），并记录边数/细胞数。 结果-ECD和细胞面积的平均值为3987细胞/ mm 2 （95 CI 3806到4168个/ mm 2 ）和278（SD 85）µm 2 ，正态分布（COV 28.2％，范围17.4 2 = 0.993），而六个侧细胞的百分数与ECD呈负相关（p <0.01，r = 0.493）。 结论—儿童的ECD较高，但这并不意味着“六边形”的比例很高。
