首页> 美国卫生研究院文献>The British Journal of Ophthalmology >Pilocarpine dispensation for the soft hydrophilic contact lens.
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Pilocarpine dispensation for the soft hydrophilic contact lens.

机译:毛果芸香碱分配剂用于柔软的亲水性隐形眼镜。

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摘要

The use of hydrophilic soft contact lenses for dispensation of pilocarpine is described. The release rate of pilocarpine from three materials of different water content was estimated and from this the surface concentrations were calculated. It is estimated that PolyHEMA can after 15 hours provide a 1 per cent surface concentration of pilocarpine, whereas higher water content materials (70 and 85 per cent) halve this, although they provide a much higher concentration in the first few hours of use. These results are based upon pre-soaking in 4 per cent pilocarpine solution. Because contact lenses present a management problem, this method of dispensation will be used only for selected cases. Some clinical examples treated successfully over a 20 month period are discussed.
机译:描述了使用亲水性软隐形眼镜分配毛果芸香碱。估计毛果芸香碱从三种不同水含量的物质中的释放速率,并据此计算表面浓度。据估计,PolyHEMA可以在15小时后提供1%的毛果芸香碱表面浓度,而含水量较高的材料(分别为70%和85%)将其减少一半,尽管它们在使用的最初几个小时内浓度要高得多。这些结果是基于预先浸泡在4%的毛果芸香碱溶液中得出的。由于隐形眼镜存在管理问题,因此这种分配方法仅适用于特定情况。讨论了在20个月内成功治疗的一些临床实例。

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