Male-typical visuospatial functioning in gynephilic girls with gender dysphoria — organizational and activational effects of testosterone

摘要

BackgroundSex differences in performance and regional brain activity during mental rotation have been reported repeatedly and reflect organizational and activational effects of sex hormones. We investigated whether adolescent girls with gender dysphoria (GD), before and after 10 months of testosterone treatment, showed male-typical brain activity during a mental rotation task (MRT).