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Pilot study of the use of community volunteers to distribute azithromycin for trachoma control in Ghana.

机译:利用社区志愿者分发阿奇霉素以控制加纳沙眼的试验研究。

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摘要

OBJECTIVE: To assess the skills of community health volunteers in diagnosing active trachoma and distributing azithromycin in the Northern Region of Ghana. METHODS: Six community health volunteers from Daboya were trained to diagnose trachoma and to treat the disease using azithromycin. They were also informed of the drug's possible side-effects. Under supervision, each volunteer then examined, and if necessary treated, 15 households. The dose of azithromycin was determined by weight; height was also measured. Tablets were given in preference to suspension when possible. RESULTS: The volunteers' diagnostic sensitivity for active trachoma was 63%; their specificity was 96%. At the household level, their "decision to treat" was correct in 83% of households. In 344 treatment episodes, volunteers planned a dose of azithromycin outside the range 15-30 mg/kg on only seven occasions (2.0% of all planned treatments). The volunteers' drug management skills were good, the response of the community was excellent, and adverse reactions were infrequent. Diagnosis of active trachoma, record-keeping skills, and knowledge of side-effects were found to need greater emphasis in any future education programme. Most people aged four years or older were able to swallow tablets. For those taking tablets, the correlation between the data gathered for height and weight shows that calculating azithromycin doses by height is a valid alternative to calculating it by weight. CONCLUSION: Trained community health volunteers have a potential role in identifying active trachoma and distributing azithromycin. To simplify training and logistics, it may be better to base dosage schedules on height rather than weight for those taking tablets, which included most people aged four years or more in the population studied.
机译:目的:评估社区卫生志愿者在加纳北部地区诊断活动性沙眼和分配阿奇霉素的技能。方法:对来自达博亚的六名社区卫生志愿者进行了培训,以诊断沙眼并使用阿奇霉素治疗该疾病。他们还被告知该药物可能产生的副作用。在监督下,每个志愿者随后检查了15户家庭,并在必要时进行了治疗。阿奇霉素的剂量按重量确定;还测量了高度。如果可能的话,优先使用片剂而不是悬浮液。结果:志愿者对活动性沙眼的诊断敏感性为63%。其特异性为96%。在家庭一级,他们的“治疗决定”在83%的家庭中是正确的。在344次治疗中,志愿者仅七次计划了超出15-30 mg / kg范围的阿奇霉素剂量(占所有计划治疗的2.0%)。志愿者的药物管理技能良好,社区反应良好,不良反应少见。活动性沙眼的诊断,记录技巧和副作用知识被发现在任何未来的教育计划中都需要得到更大的重视。大多数四岁或四岁以上的人都可以吞咽药片。对于服用药片的人,身高和体重数据的相关性表明,按身高计算阿奇霉素剂量是替代按体重计算的有效选择。结论:训练有素的社区卫生志愿者在识别活动性沙眼和分配阿奇霉素方面具有潜在作用。为了简化培训和后勤工作,对于服用片剂的人,最好将身高剂量表而不是体重作为基础,其中包括大多数年龄在4岁或以上的人群。

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