Principles of malaria vaccine trials: Memorandum from a WHO Meeting

摘要

The Scientific Working Groups on Immunology of Malaria and on Applied Field Research in Malaria of the UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases held a joint meeting at WHO headquarters in Geneva, Switzerland, on 4-8 February 1985 to consider the current status of malaria vaccine research. Although experience with vaccines against bacterial and viral infections provides valuable information, the advanced stages of development of malaria vaccines pose entirely new problems calling for the elaboration of guidelines for preclinical studies and vaccine trials. The principal purpose of this meeting was to establish such guidelines.