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Recent Progress in the Theranostics Application of Nanomedicine in Lung Cancer

机译:纳米药物在肺癌治疗中的最新研究进展

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摘要

Lung cancer is one of the leading causes of cancer-related death worldwide. Non-small cell lung cancer (NSCLC) causes around 80% to 90% of deaths. The lack of an early diagnosis and inefficiency in conventional therapies causes poor prognosis and overall survival of lung cancer patients. Recent progress in nanomedicine has encouraged the development of an alternative theranostics strategy using nanotechnology. The interesting physico-chemical properties in the nanoscale have generated immense advantages for nanoparticulate systems for the early detection and active delivery of drugs for a better theranostics strategy for lung cancer. This present review provides a detailed overview of the recent progress in the theranostics application of nanoparticles including liposomes, polymeric, metal and bio-nanoparticles. Further, we summarize the advantages and disadvantages of each approach considering the improvement for the lung cancer theranostics.
机译:肺癌是全世界与癌症相关的死亡的主要原因之一。非小细胞肺癌(NSCLC)导致约80%至90%的死亡。缺乏早期诊断和传统疗法的无效导致肺癌患者的不良预后和总体生存。纳米医学的最新进展鼓励了使用纳米技术的另一种治疗学策略的发展。纳米级有趣的物理化学特性为纳米颗粒系统提供了巨大的优势,可用于早期检测和主动递送药物,从而更好地治疗肺癌。这篇综述提供了包括脂质体,聚合物,金属和生物纳米颗粒在内的纳米颗粒在肿瘤治疗中的最新进展的详细概述。此外,我们总结了每种方法的优缺点,考虑了肺癌治疗学的改进。

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