Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab

机译：HER-2高表达胆道癌对曲妥珠单抗的明显放射学反应

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摘要

Trastuzumab is a monoclonal antibody targeting HER-2. HER-2 overexpression has been described in gallbladder cancer and in cholangiocarcinoma. This report describes the first case of a patient with HER-2 overexpressing metastatic gallbladder adenocarcinoma and responding radiographically and biochemically to trastuzumab alone.

机译：曲妥珠单抗是靶向HER-2的单克隆抗体。 HER-2过表达已在胆囊癌和胆管癌中描述。该报告描述了第一例HER-2过表达转移性胆囊腺癌并对放射线和生化反应单独对曲妥珠单抗有反应的患者。

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期刊名称 Cancer Management and Research
作者
Steven Sorscher;
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作者单位

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年(卷),期 2014(9),-1
年度 2014
页码 1–3
总页数 3
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
metastatic gallbladder adenocarcinoma HER-2 overexpression trastuzumab;

机译：转移性胆囊腺癌;HER-2过表达;曲妥珠单抗;

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专利

1. 曲妥珠单抗联合多西紫杉醇治疗Her-2/neu高表达转移性乳腺癌的疗效和不良反应 [J] . 周宁宁, 林旭滨, 刘冬耕, 癌症（英文版） . 2008,第009期
2. Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab [J] . Steven Sorscher Cancer Management and Research . 2014,第2016期

机译：HER-2高表达胆道癌对曲妥珠单抗的明显放射学反应
3. CD40 signaling predicts response to preoperative trastuzumab and concomitant paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide in HER-2-overexpressing breast cancer [J] . Francisco J Esteva, Jing Wang, Feng Lin, Breast Cancer Research . 2007,第6期

机译：CD40信号传导可预测在过表达HER-2的乳腺癌中对术前曲妥珠单抗和伴随的紫杉醇，5-氟尿嘧啶，表柔比星和环磷酰胺的反应
4. 5021 Everolimus (RAD001) in combination with weekly paclitaxel and trastuzumab in patients (pts) with HER-2-overexpressing metastatic breast cancer (MBC) with prior resistance to trastuzumab: a multicenter phase I clinical trial [J] . S.Hurvitz, R.ORegan, M.Campone, European Journal of Cancer Supplements . 2009,第2期

机译：5021依维莫司（RAD001）与每周紫杉醇和曲妥珠单抗联合治疗对先前对曲妥珠单抗有耐药性的HER-2过表达转移性乳腺癌（MBC）的患者（pts）：一项多中心I期临床试验
5. Elevated WBP2 Expression in HER2-Positive Breast Cancers Correlates with Sensitivity to Trastuzumab-Based Neo-Adjuvant Therapy: A Retrospective and Multicentric Study [C] . Yoon Pin Lim International Molecular Medicine Tri-Conference. . 2019

机译：HER2阳性乳腺癌中的WBP2表达升高与基于曲妥珠单抗的新辅助治疗的敏感性相关：回顾性和多中心研究
6. Gut Microbiota and Trastuzumab Response in HER2-Positive Breast Cancer [D] . Di Modica, Martina. 2020

机译：肠道微生物群和胸瘤反应在Her2阳性乳腺癌中
7. CD40 signaling predicts response to preoperative trastuzumab and concomitant paclitaxel followed by 5-fluorouracil epirubicin and cyclophosphamide in HER-2-overexpressing breast cancer [O] . Francisco J Esteva, Jing Wang, Feng Lin, 2007

机译：CD40信号传导可预测对HER-2过表达的乳腺癌患者术前曲妥珠单抗和伴随的紫杉醇5-氟尿嘧啶表柔比星和环磷酰胺的反应
8. Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab [O] . Sorscher Steven 2013

机译：HER-2高表达胆道癌对曲妥珠单抗的明显放射学反应

Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab

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