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The Wrong Turn to Tijuana: Dry Beriberi after Gastric Bypass Surgery with Incidental Spinal Stenosis

机译:错误地转向蒂华纳州:伴有偶然性椎管狭窄的胃旁路手术后干性贝贝

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摘要

Thiamine deficiency is a condition characterized by several different presentations, but one of the most devastating is dry beriberi. It is associated with polyneuropathy and muscle weakness which typically affects the lower extremities and progressively involves the upper extremities. This case outlines a case of a 41-year-old man that presented to the hospital with diffuse weakness and decreased sensation in his legs and hands over a 3-day period. The patient's medical history revealed a gastric bypass surgery 4 months previously in Tijuana, Mexico, with no follow-up, binge drinking on weekends, and emesis in the past few weeks. A physical examination revealed a significant decrease in strength in the lower extremities bilaterally as well as in the hands bilaterally. MRI showed central disc protrusion at T6–T7 that indented the spinal cord, consistent with spinal stenosis. Neurosurgery was counseled and corpectomy was recommended. While awaiting surgery, a low thiamine level resulted. Neurology was consulted, and it was recommended that high-dose IV thiamine treatment be started. An EMG study further supported the diagnosis of thiamine deficiency. The patient received high-dose IV thiamine for 2 weeks and was discharged to acute rehabilitation on a high oral dose of thiamine. While at the rehabilitation facility, the patient continued to achieve functional gains and was later discharged to a skilled nursing facility, where he continues to make progress in his activities of daily living. This case serves to remind practitioners that early recognition and treatment of thiamine deficiency is imperative, especially when other clinical evidence may point to a different diagnosis.
机译:硫胺素缺乏症是一种以几种不同表现形式为特征的疾病,但最具破坏性的一种是干燥脚气病。它与多发性神经病和肌肉无力相关,通常影响下肢并逐渐累及上肢。该病例概述了一名41岁男子的情况,该男子在3天的时间内出现弥漫性肌无力且腿部和手部感觉减退的医院。患者的病史显示,在墨西哥蒂华纳(Tijuana),四个月前进行了胃旁路手术,没有随访,周末暴饮暴食,过去几周呕吐。体格检查发现双侧下肢以及双侧双手的力量明显下降。 MRI显示T6-T7处的中央椎间盘突出,使脊髓缩进,与脊髓狭窄相符。建议进行神经外科手术,并建议行体切除术。在等待手术时,硫胺素水平较低。咨询了神经内科,建议开始大剂量静脉注射硫胺素治疗。一项肌电图研究进一步支持了硫胺素缺乏症的诊断。该患者接受了大剂量的静脉注射硫胺素治疗2周,并因口服高剂量的硫胺素而出院进行急性康复。在康复机构期间,患者继续获得功能改善,随后被送往熟练的护理机构,在那里他的日常生活活动继续取得进展。该案例提醒从业者,硫胺素缺乏症的早期识别和治疗势在必行,特别是在其他临床证据可能指向不同诊断的情况下。

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