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Dealing with Pheochromocytoma during the First Trimester of Pregnancy

机译:在怀孕的前三个月处理嗜铬细胞瘤

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摘要

Purpose. Pheochromocytoma in association with pregnancy is a very rare, without specific symptoms, life-threatening condition, increasing both maternal and fetal mortality up to 50%. The present paper illustrates the case of a pregnant woman, diagnosed with pheochromocytoma, aiming to demonstrate and discuss the difficulties that arouse during the diagnosis and the problems concerning the treatment. Patient. A 34-year-old woman, in the 9th week of pregnancy, complained for headache, sweating, and a feeling of heavy weight on the right renal area. A tumor of 10 cm diameter at the site of the right adrenal was found. Twenty-four-hour urine catecholamine and VMA excretion levels were well raised. Results. Multidisciplinary approach treated the patient conservatively. Surgical resection of the tumor was performed after the 14th week of pregnancy at the completion of organogenesis. Neither postoperative complications occurred nor hypertension relapse was recorded. The fetus was delivered without complications at the 36th week. Conclusions. There are no consensus and guidelines for treating pheochromocytoma during pregnancy, especially when it is diagnosed in the first trimester. The week of pregnancy and a multidisciplinary approach will determine whether the pregnancy should be continued or not, as well as the time and the approach of surgical treatment.
机译:目的。与妊娠相关的嗜铬细胞瘤非常罕见,没有特定的症状,危及生命,将孕产妇和胎儿的死亡率都提高了50%。本文阐述了一名孕妇,被诊断为嗜铬细胞瘤,旨在证明和讨论诊断过程中引起的困难以及与治疗有关的问题。患者。一名34岁的妇女在怀孕的第9周,抱怨头痛,出汗以及右肾区域有重物。在右肾上腺部位发现直径为10厘米的肿瘤。二十四小时尿儿茶酚胺和VMA排泄水平升高。结果。多学科方法保守地对待患者。妊娠第14周后器官发生完成后,进行肿瘤的手术切除。既没有术后并发症的发生,也没有高血压复发的记录。胎儿在​​第36周分娩而没有并发症。结论。目前尚无关于治疗妊娠期嗜铬细胞瘤的共识和指南,尤其是在妊娠早期诊断出嗜铬细胞瘤时。妊娠的一周和多学科的方法将决定是否应该继续妊娠,以及手术治疗的时间和方法。

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