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Limb Ischemia after Heart Transplantation: An Unusual Case of Tissue Embolism

机译:心脏移植后的肢体缺血:组织栓塞的罕见病例

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摘要

Major complications of heart transplantation include graft rejection, infection, graft arteriosclerosis, malignancy, and drug toxicity. Among these complications, infections and thrombophilic disorders are of particular interest owing to their major contribution to morbidity and mortality among heart transplantation patients. Thrombophilic disorders are caused by imbalance between hypercoagulation and fibrinolytic states. In this report, we describe a 43-year-old man who had unusual complications of heart transplantation. We presume that the unusual postoperative complications of the patient might have been caused by a faulty surgical procedure, improper use of anticoagulant agents, and incomplete prophylaxis for infections. During the postoperative period, the patient suffered arterial obstruction three times, for which he underwent clot removal via embolectomy. In addition to arterial obstruction, the patient had a mobile mass in the left atrium that was removed by open cardiac surgery. The frozen sample of the cardiac mass was positive for Acinetobacter baumannii. After 7 days of observation in the hospital and proper antibiotic regimen, the patient was sent home with no additional complaints and normal physical examination. We conclude that in heart transplantation patients, the precise performance of the surgical procedure, postoperative care, and early removal of the embolus might reduce morbidities and mortality due to thrombophilic disorders.
机译:心脏移植的主要并发症包括移植排斥,感染,移植性动脉硬化,恶性肿瘤和药物毒性。在这些并发症中,由于感染和血栓形成性疾病对心脏移植患者的发病率和死亡率起主要作用,因此特别引起人们的关注。血栓形成性疾病是由高凝状态和纤溶状态之间的不平衡引起的。在本报告中,我们描述了一名43岁的男子,他患有心脏移植的异常并发症。我们认为患者异常的术后并发症可能是由于外科手术程序错误,抗凝剂使用不当以及对感染的预防不完全所致。在术后期间,该患者遭受了三次动脉阻塞,为此他通过栓塞切除术去除了血凝块。除动脉阻塞外,患者左心房有一块可移动的肿物,该肿物已通过心脏直视手术切除。心脏质量的冷冻样品鲍曼不动杆菌呈阳性。在医院进行了7天的观察并采取了适当的抗生素治疗方案后,该患者被送回家中,没有其他不适,体格检查正常。我们得出的结论是,在心脏移植患者中,手术过程,术后护理和早期清除栓子的精确性能可能会降低由于血栓形成性疾病而导致的发病率和死亡率。

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