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Exosomal MicroRNA-10a Is Associated with Liver Regeneration in Rats through Downregulation of EphA4

机译：外泌体microRNA-10a通过下调EphA4与大鼠肝脏再生相关。

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Background:MicroRNAs (miRNAs) have been reported to play vital roles in liver regeneration. Previous studies mainly focused on the functions of intracellular miRNAs, while the functions of circulating exosomal miRNAs in liver regeneration remain largely unknown. The aim of this study was to identify the key exosomal miRNA that played vital roles in liver regeneration.

机译：背景：据报道，微小RNA（miRNA）在肝脏再生中起着至关重要的作用。先前的研究主要集中在细胞内miRNA的功能上，而循环外泌体miRNA在肝脏再生中的功能仍然未知。这项研究的目的是确定在肝再生中起关键作用的关键外泌体miRNA。

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期刊名称 Chinese Medical Journal
作者
Lin Luo; Ze-Ping Yu; Han Qin; Ze-Xin Zhu; Ming-Heng Liao; Hao-Tian Liao; Ke-Fei Yuan; Yong Zeng;
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作者单位

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年(卷),期 2018(131),4
年度 2018
页码 454–460
总页数 8
原文格式 PDF
正文语种
中图分类基础医学;
关键词
Cell Cycle EphA4 Liver Regeneration Microarray miR-10a;

机译：细胞周期;EphA4;肝再生;微阵列;miR-10a;

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专利

1. Exosomal MicroRNA-10a Is Associated with Liver Regeneration in Rats through Downregulation of EphA4 [J] . Lin Luo, Ze‑Ping Yu, Han Qin, 中华医学杂志（英文版） . 2018,第004期

机译：外泌体MicroRNA-10a通过下调EphA4与大鼠肝脏再生相关。
2. Disruptive cell cycle regulation involving epigenetic downregulation of Cdkn2a (p16 Ink4a) in early-stage liver tumor-promotion facilitating liver cell regeneration in rats [J] . TsuchiyaT., WangL., YafuneA., Toxicology: An International Journal Concerned with the Effects of Chemicals on Living Systems . 2012,第2a3期

机译：早期肝肿瘤促进中涉及Cdkn2a（p16 Ink4a）表观遗传下调的破坏性细胞周期调控，促进大鼠肝细胞再生
3. Transcriptional regulation of alpha(1b) adrenergic receptors (alpha(1b)AR) by nuclear factor 1 (NF1): a decline in the concentration of NF1 correlates with the downregulation of alpha(1b)AR gene expression in regenerating liver. [J] . B Gao, L Jiang, G Kunos Molecular and Cellular Biology . 1996,第11期

机译：核因子1（NF1）对α（1b）肾上腺素受体（alpha（1b）AR）的转录调控：NF1浓度的下降与再生肝中alpha（1b）AR基因表达的下调有关。
4. Liver Regenerative Medicine and In Vivo Molecular Imaging for the Study of In Vivo Liver Organogenesis, Liver Disease and Development of New Diagnostics and Therapeutics [C] . Natesh Parashurama AIChE Annual Meeting . 2014

机译：肝脏再生医学和体内分子成像研究体内肝动机，肝病和新诊断和治疗方法的研究
5. Cholangiocyte marker positive and negative fetal liver cells differ significantly in their ability to regenerate the livers of adult rats exposed to retrorsine. [D] . Simper Ronan, Rhonda. 2007

机译：胆管细胞标记物阳性和阴性胎儿肝细胞再生暴露于逆转录酶的成年大鼠肝脏的能力显着不同。
6. Transcriptional regulation of alpha(1b) adrenergic receptors (alpha(1b)AR) by nuclear factor 1 (NF1): a decline in the concentration of NF1 correlates with the downregulation of alpha(1b)AR gene expression in regenerating liver. [O] . B Gao, L Jiang, G Kunos 1996

机译：核因子1（NF1）对α（1b）肾上腺素能受体（alpha（1b）AR）的转录调控：NF1浓度的下降与再生肝中alpha（1b）AR基因表达的下调有关。
7. Exosomal MicroRNA-10a Is Associated with Liver Regeneration in Rats through Downregulation of EphA4 [O] . Lin Luo, Ze-Ping Yu, Han Qin, 2018

机译：外泌体microRNA-10a与大鼠肝再生通过Epha4的下调有关
8. THE EFFECT OF VARYING DOSES OF CORTISOL ON THE INCORPORATION OF 3H-THYMIDINE INTO RAT LIVER DNA AND ON THE SYNTHESIS OF FIVE PLASMA PROTEINS IN THE ISOLATED PERFUSED REGENERATING RAT LIVER [R] . Nancy Jean Abbott Lebda 1972

机译：不同剂量的CORTIsOL对3H-甲脒加入大鼠肝脏DNa的影响及离体再灌注大鼠肝脏中5种血浆蛋白质的合成

Exosomal MicroRNA-10a Is Associated with Liver Regeneration in Rats through Downregulation of EphA4

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