首页> 美国卫生研究院文献>Journal of Translational Medicine >Dose-dependent effects of NY-ESO-1 protein vaccine complexed with cholesteryl pullulan (CHP-NY-ESO-1) on immune responses and survival benefits of esophageal cancer patients

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Dose-dependent effects of NY-ESO-1 protein vaccine complexed with cholesteryl pullulan (CHP-NY-ESO-1) on immune responses and survival benefits of esophageal cancer patients

机译：NY-ESO-1蛋白疫苗与胆固醇支链淀粉（CHP-NY-ESO-1）配合使用对食管癌患者免疫应答和生存获益的剂量依赖性作用

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摘要

BackgroundCholesteryl pullulan (CHP) is a novel antigen delivery system for cancer vaccines. This study evaluated the safety, immune responses and clinical outcomes of patients who received the CHP-NY-ESO-1 complex vaccine, Drug code: IMF-001.

机译：背景胆固醇支链淀粉（CHP）是用于癌症疫苗的新型抗原递送系统。这项研究评估了接受CHP-NY-ESO-1复合疫苗（药物代码：IMF-001）的患者的安全性，免疫反应和临床结局。

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期刊名称 Journal of Translational Medicine
作者
Shinichi Kageyama; Hisashi Wada; Kei Muro; Yasumasa Niwa; Shugo Ueda; Hiroshi Miyata; Shuji Takiguchi; Sahoko H Sugino; Yoshihiro Miyahara; Hiroaki Ikeda; Naoko Imai; Eiichi Sato; Tomomi Yamada; Masaharu Osako; Mami Ohnishi; Naozumi Harada; Tadashi Hishida; Yuichiro Doki; Hiroshi Shiku;
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作者单位

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年(卷),期 2013(11),-1
年度 2013
页码 246
总页数 10
原文格式 PDF
正文语种
中图分类医学史;
关键词
Esophageal cancer Cancer vaccine NY-ESO-1 Cholesteryl pullulan (CHP);

机译：食道癌;癌症疫苗;NY-ESO-1;胆固醇支链淀粉（CHP）;

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外文文献
专利

1. Dose-dependent effects of NY-ESO-1 protein vaccine complexed with cholesteryl pullulan (CHP-NY-ESO-1) on immune responses and survival benefits of esophageal cancer patients [J] . Shinichi Kageyama, Hisashi Wada, Kei Muro, Journal of Translational Medicine . 2013,第1期

机译：NY-ESO-1蛋白疫苗与胆固醇支链淀粉（CHP-NY-ESO-1）配合使用对食道癌患者免疫应答和生存获益的剂量依赖性作用
2. Antibody responses against NY-ESO-1 and HER2 antigens in patients vaccinated with combinations of cholesteryl pullulan (CHP)-NY-ESO-1 and CHP-HER2 with OK-432. [J] . Aoki M., Ueda S., Nishikawa H., Vaccine . 2009,第49期

机译：接种胆固醇基支链淀粉（CHP）-NY-ESO-1和CHP-HER2与OK-432组合疫苗的患者对NY-ESO-1和HER2抗原的抗体反应。
3. Humoral immune responses in patients vaccinated with 1-146 HER2 protein complexed with cholesteryl pullulan nanogel. [J] . Kageyama S, Kitano S, Hirayama M, Cancer science. . 2008,第3期

机译：接种了1-146 HER2蛋白和胆固醇基支链淀粉纳米凝胶的患者的体液免疫反应。
4. Predictive value of FDG uptake on survival of patients with early and late stage esophageal cancer [C] . The First China-Japan-Korea conference of nuclear medicine . 2002

机译：FDG摄取对早期和晚期食管癌患者生存的预测价值
5. The Effects of Dietary Protein on the Response to Vaccine in Individuals at Risk of Immune Senescence [D] . Fischer, Laura K. 2013

机译：膳食蛋白对具有免疫衰老风险的个体对疫苗反应的影响
6. T cell immunomonitoringand tumor responses in patients immunized with a complex of cholesterol-bearinghydrophobized pullulan (CHP) and NY-ESO-1 protein [O] . Akiko Uenaka, Hisashi Wada, Midori Isobe, 2007

机译：T细胞免疫监测含胆固醇复合物免疫的患者的肿瘤和肿瘤反应疏水性支链淀粉（CHP）和NY-ESO-1蛋白
7. Dose-dependent effects of NY-ESO-1 protein vaccine complexed with cholesteryl pullulan (CHP-NY-ESO-1) on immune responses and survival benefits of esophageal cancer patients [O] . Shinichi Kageyama, Hisashi Wada, Kei Muro, 2013

机译：NY-ESO-1蛋白疫苗与胆固醇支链淀粉（CHP-NY-ESO-1）配合使用对食管癌患者免疫应答和生存获益的剂量依赖性作用

Dose-dependent effects of NY-ESO-1 protein vaccine complexed with cholesteryl pullulan (CHP-NY-ESO-1) on immune responses and survival benefits of esophageal cancer patients

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