Circulating miRNAs as non-invasive biomarkers to predict aggressive prostate cancer after radical prostatectomy

摘要

BackgroundProstate cancer is an extremely heterogeneous disease. Despite being clinically similar, some tumours are more likely to recur after surgery compared to others. Distinguishing those that need adjuvant or salvage radiotherapy will improve patient outcomes. The goal of this study was to identify circulating microRNA that could independently predict prostate cancer patient risk stratification after radical prostatectomy.