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A randomized phase II trial of mitoxantrone estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899

机译：米托蒽醌雌莫司汀和长春瑞滨或bcl-2联合13-顺式视黄酸干扰素和紫杉醇对转移性去势抵抗性前列腺癌患者的II期随机试验：ECOG 3899

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BackgroundTo test the hypothesis that modulation of Bcl-2 with 13-cis retinoic acid (CRA)/interferon-alpha2b (IFN) with paclitaxel (TAX), or mitoxantrone, estramustine and vinorelbine (MEV) will have clinical activity in men with metastatic castrate-resistant prostate cancer (CRPC).

机译：背景为了检验以下假设，即用13-顺式视黄酸（CRA）/干扰素-α2b（IFN）和紫杉醇（TAX）或米托蒽醌，雌莫司汀和长春瑞滨（MEV）调节Bcl-2在转移去势男性中具有临床活性耐药性前列腺癌（CRPC）。

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期刊名称 Journal of Translational Medicine
作者
Robert S DiPaola; Yu-Hui Chen; Mark Stein; David Vaughn; Linda Patrick-Miller; Michael Carducci; Bruce Roth; Eileen White; George Wilding;
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年(卷),期 2010(8),-1
年度 2010
页码 20
总页数 9
原文格式 PDF
正文语种
中图分类医学史;
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机译：米托蒽醌，雌莫司汀和长春瑞滨或bcl-2联合13-顺式视黄酸，干扰素和紫杉醇对转移性去势抵抗性前列腺癌患者的II期随机试验：ECOG 3899
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机译：多西紫杉醇联合或不联合PSA-TRICOM疫苗在去势抵抗性转移性前列腺癌患者中的II期随机试验：ECOG-ACRIN癌症研究小组的一项试验（E1809）
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机译：米托蒽醌，雌莫司汀和长春瑞滨或bcl-2联合13-顺式视黄酸，干扰素和紫杉醇在转移性去势抵抗性前列腺癌患者中的II期随机试验：ECOG 3899
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A randomized phase II trial of mitoxantrone estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899

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