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Bioresorbable vascular scaffolds in patients with acute myocardial infarction: a new step forward to optimized reperfusion?

机译:急性心肌梗死患者的生物可吸收血管支架:优化再灌注的新步骤?

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摘要

Bioresorbable vascular scaffolds (BVS) represent a disruptive technology that has caused a new revolution in interventional cardiology. BVS appear to be particularly appealing in patients presenting with an acute myocardial infarction (MI). The available evidence on the value of BVS implantation in this challenging scenario is very promising but still limited. Results come from preliminary small observational studies, prospective registries that include a control group, and from scarce randomized clinical trials with surrogate mechanistic or angiographic primary end-points. Further studies, powered for clinical endpoints, are required to establish the relative safety and efficacy of BVS vs. new-generation metallic drug-eluting stents (DES) in patients with ST-segment elevation acute MI.
机译:可生物吸收的血管支架(BVS)代表了一种破坏性技术,已引起介入心脏病学的新革命。 BVS在患有急性心肌梗塞(MI)的患者中似乎特别有吸引力。在这种具有挑战性的情况下,有关BVS植入价值的现有证据非常有前途,但仍然有限。结果来自初步的小型观察性研究,包括对照组的前瞻性注册研究,以及来自缺乏替代机制或血管造影主要终点的随机临床试验。需要针对临床终点的进一步研究,以建立BVS与新一代ST段抬高急性MI患者相对于新一代金属药物洗脱支架(DES)的相对安全性和有效性。

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