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Solid-state characterization of triamcinolone acetonide nanosuspensiones by X-ray spectroscopy ATR Fourier transforms infrared spectroscopy and differential scanning calorimetry analysis

机译:X射线光谱法ATR傅里叶变换红外光谱法和差示扫描量热分析法对曲安奈德纳米悬浮液进行固态表征

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摘要

The data presented in this article describe the physical state of the triamcinolone acetonide (TA) in nanosuspension stabilized with polyvinyl alcohol (PVA) and poloxamer 407 (PL). The data were assessed by X-ray spectroscopy, ATR Fourier transforms infrared spectroscopy measurements (FTIR), and Differential scanning calorimetry (DSC) analysis. PVA, PL and polymeric mixture (PVA and PL) were compared with nanosuspension and the interactions between drug triamcinolone acetonide and polymers were studied. The data are related and are complementary to the research article entitle “Improved release of triamcinolone acetonide from medicated soft contact lenses loaded with drug nanosuspensions” (García-Millán et al., 2017) .
机译:本文提供的数据描述了用聚乙烯醇(PVA)和泊洛沙姆407(PL)稳定的纳米悬浮液中曲安奈德(TA)的物理状态。通过X射线光谱,ATR傅立叶变换红外光谱测量(FTIR)和差示扫描量热法(DSC)分析评估数据。将PVA,PL和聚合物混合物(PVA和PL)与纳米悬浮液进行了比较,并研究了药物曲安奈德丙酮与聚合物之间的相互作用。这些数据是相关的,并且与题为“曲安奈德从载有药物纳米混悬剂的含药软性隐形眼镜的释放得到改善”的研究文章互补(García-Millán等人,2017)。

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