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Expression Profiles of the Individual Genes Corresponding to the Genes Generated by Cytotoxicity Experiments with Bortezomib in Multiple Myeloma

机译：在多发性骨髓瘤中与硼替佐米的细胞毒性实验产生的基因相对应的单个基因的表达谱

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Objective:Multiple myeloma (MM) is currently incurable due to refractory disease relapse even under novel anti-myeloma treatment. In silico studies are effective for key decision making during clinicopathological battles against the chronic course of MM. The aim of this present in silico study was to identify individual genes whose expression profiles match that of the one generated by cytotoxicity experiments for bortezomib.

机译：目的：即使在新型抗骨髓瘤治疗下，由于难治性疾病复发，目前仍无法治愈多发性骨髓瘤（MM）。在针对MM慢性病的临床病理斗争中，计算机模拟研究对于关键决策有效。本计算机模拟研究的目的是鉴定表达谱与硼替佐米的细胞毒性实验产生的表达谱相匹配的单个基因。

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期刊名称 Turkish Journal of Hematology
作者
Mehdi Ghasemi; Semih Alpsoy; Seyhan Türk; Ümit Y. Malkan; Şükrü Atakan; İbrahim C. Haznedaroğlu; Gürsel Güneş; Mehmet Gündüz; Burak Yılmaz; Sezgin Etgül; Seda Aydın; Tuncay Aslan; Nilgün Sayınalp; Salih Aksu; Haluk Demiroğlu; Osman İ. Özcebe; Yahya Büyükaşık; Hakan Göker;
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作者单位

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年(卷),期 2016(33),4
年度 2016
页码 286–292
总页数 7
原文格式 PDF
正文语种
中图分类血液学检验;
关键词
Myeloma and other plasma cell dyscrasias Neoplasia cytogenetics gene therapy Molecular hematology;

机译：骨髓瘤和其他浆细胞异常;肿瘤;细胞遗传学;基因治疗;分子血液学;

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1. Expression Profiles of the Individual Genes Corresponding to the Genes Generated by Cytotoxicity Experiments with Bortezomib in Multiple Myeloma [J] . Myeloma, other plasma cell dyscrasias, Neoplasia, Turkish Journal of Hematology . 2016,第4期

机译：在多发性骨髓瘤中与硼替佐米的细胞毒性实验产生的基因相对应的单个基因的表达谱
2. Dendritic cells loaded with myeloma cells pretreated with a combination of JSI-124 and bortezomib generate potent myeloma-specific cytotoxic T lymphocytes in vitro [J] . JungS.-H., LeeY.-K., LeeH.-J., Experimental Hematology: Official Publication of the International Society for Experimental Hematology . 2014,第4期

机译：结合了JSI-124和硼替佐米预处理的骨髓瘤细胞的树突状细胞在体外产生有效的骨髓瘤特异性细胞毒性T淋巴细胞
3. Myeloma-specific multiple peptides able to generate cytotoxic T lymphocytes: A potential therapeutic application in multiple myeloma and other plasma cell disorders [J] . Clinical cancer research: an official journal of the American Association for Cancer Research . 2012,第17期

机译：骨髓瘤特异性多肽能够产生细胞毒性T淋巴细胞：在多发性骨髓瘤和其他浆细胞疾病中的潜在治疗应用
4. Profiling Multiple Myeloma: Correlation of Protein and Gene Expression Data [C] . Ricky D. Edmondson, Veronica MacLeod, Damir Herman, ASMS Conference on Mass Spectrometry and Allied Topics . 2008

机译：分析多发性骨髓瘤：蛋白质和基因表达数据的相关性
5. Single nucleotide polymorphisms in cancer related genes lead to inter-individual response to prognosis, disease risk and environmental agent metabolism in multiple myeloma and lung cancer. [D] . Haznadar, Majda. 2010

机译：癌症相关基因中的单核苷酸多态性导致对多发性骨髓瘤和肺癌的预后，疾病风险和环境因素代谢的个体间反应。
6. Myeloma-specific multiple peptides able to generate cytotoxic T lymphocytes: A potential therapeutic application in multiple myeloma and other plasma cell disorders [O] . Jooeun Bae, Robert Smith, John Daley, -1

机译：骨髓瘤特异性多肽能够产生细胞毒性T淋巴细胞：多种骨髓瘤和其他血浆细胞紊乱中的潜在治疗应用
7. Expression Profiles of the Individual Genes Corresponding to the Genes Generated by Cytotoxicity Experiments with Bortezomib in Multiple Myeloma [O] . Mehdi Ghasemi, Semih Alpsoy, Seyhan Türk, 2016

机译：与多发性骨髓瘤中硼替佐米细胞毒性实验相关基因的个体基因表达谱

Expression Profiles of the Individual Genes Corresponding to the Genes Generated by Cytotoxicity Experiments with Bortezomib in Multiple Myeloma

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