首页> 美国卫生研究院文献>Journal of Neurological Surgery Reports >Osteolysis and Cervical Cord Compression Secondary to Silicone Granuloma Formation around a Dorsal Spinal Cord Stimulator: A Case Report
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Osteolysis and Cervical Cord Compression Secondary to Silicone Granuloma Formation around a Dorsal Spinal Cord Stimulator: A Case Report

机译:继发于脊髓脊髓刺激器周围的硅胶肉芽肿形成继发的骨溶解和颈椎受压:一例报告

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摘要

Spinal cord stimulators (SCSs) have long been in use as a modality for the management of numerous pain pathologies. Along with commonly anticipated morbidities such as displacement, failure (due to fracture or breakage), or infection, there have also been rare but well-documented complications of fibrous scarring, resulting in spinal cord compression. This is the first known case that demonstrates osteolysis and bony destruction of the vertebrae adjacent to the SCS along with the foreign-body granulomatous reaction. A 61-year-old man who underwent prior posterior cervical implantation with an SCS followed by multiple revisions presented with progressive paresthesias, numbness, and weakness of his upper extremities 10 years later. The SCS was removed followed by decompression, and instrumented fusion of the cervical spine. Histopathologic analysis reveals foreign-body reaction to the SCS and its silicone debris. Tissue cultures were negative for bacterial, fungal, or mycobacterial infection. No malignancy was seen. The current case illustrates the inherent possibility of foreign-body granulomatous reactions with SCS and its silicone particulate matter, made unique in this instance by the associated bony destruction of the adjacent vertebrae.
机译:长期以来,脊髓刺激器(SCS)一直被用作治疗多种疼痛病理的手段。除了通常预期的发病率,例如移位,衰竭(由于骨折或折断)或感染外,还很少见但有据可查的纤维疤痕并发症,导致脊髓受压。这是第一个已知病例,该病例显示出与SCS相邻的椎骨发生骨溶解和骨破坏以及异物肉芽肿反应。一名61岁的男性,在接受颈椎后路植入后先行SCS,随后多次翻修,十年后出现进行性感觉异常,麻木和上肢无力。去除SCS,然后减压,并用器械融合颈椎。组织病理学分析显示异物对SCS及其有机硅碎片产生反应。组织培养对细菌,真菌或分枝杆菌感染呈阴性。未见恶性肿瘤。当前的情况说明了与SCS及其硅酮颗粒物质发生异物肉芽肿反应的内在可能性,这种情况在这种情况下是由于相邻椎骨的骨破坏而变得独特的。

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