The impact of balanced reciprocal translocation - 46XXt(7;17)(p13;q24) probably involving the SOX9 gene in the in vitrofertilization with own oocytes evaluated by preimplantation genetic testing ordonated oocytes

摘要

Preimplantation genetic testing (PGT) for in vitro fertilization (IVF) - also known as PGT for Structural Rearrangements (PGT-SR) - has emerged as an option for at-risk couples carrying balanced translocations. The female in the couple featured in this case report is a carrier of a balanced reciprocal translocation who underwent IVF. PGT showed all her embryos were aneuploid. She subsequently had two cycles using donor oocytes, which ended in miscarriages.