Mutant Mouse Models: Phenotypic Relationships to Domains of Psychopathology and Pathobiology in Schizophrenia

摘要

The present series of review articles seeks to elaborate how current findings in mutant mice may inform on the relationship between candidate genes and individual psychopathological and pathobiological aspects of schizophrenia. Each of the authors focuses on an overlapping selection of both well-characterized and emergent candidate genes, as identified through association and linkage studies and/or via their involvement in putative pathophysiological mechanisms, particularly those relating to dopaminergic and glutamatergic processes.