Analysis of oxidative status and biochemical parameters in adult patients with sickle cell anemia treated with hydroxyurea Ceará Brazil

摘要

BackgroundSickle cell anemia is a hemoglobinopathy caused by a mutation that results in the production of an abnormal hemoglobin molecule, hemoglobin S (Hb S). This is responsible for profound physiological changes, such as the sickling of red blood cells. Several studies have shown that hydroxyurea protects against vaso-occlusive crises.