An incidentally found solid solitary pulmonary nodule (SPN) was studied using FDG PET/CT. The SPN (at that time 11mm) showed only minimal FDG uptake, with a maximum standardized uptake value of 1.7 (max SUV). This suggested a benign lesion. When followup CT was performed six months later, the SPN had grown to 12mm. The patient was re-examined by FDG PET/CT five months later to exclude malignancy. The SPN was now FDG avid, and its size was 14mm. The max SUV was 12.7, consistent with a malignant disease. The patient underwent surgery, and histological examination demonstrated a solid adenocarcinoma (gradus III). The increase in glucose metabolism can be attributed to a change in the histopathologic subtype or molecular features of the SPN. The importance of a followup of nonmetabolically active SPNs is emphasized, primarily by CT (due to its convenience and low cost).
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机译：使用FDG PET / CT研究了偶然发现的孤立性孤立性肺结节（SPN）。 SPN（当时为11mm）仅显示了最小的FDG吸收，最大标准化吸收值为1.7（最大SUV）。这表明是良性病变。六个月后进行了后续CT检查时，SPN已长至12mm。 5个月后，通过FDG PET / CT对患者进行了再次检查，以排除恶性肿瘤。 SPN现在非常适合FDG，其尺寸为14毫米。最大SUV为12.7，与恶性疾病一致。该患者进行了手术，组织学检查显示为实体腺癌（III级）。葡萄糖代谢的增加可归因于SPN的组织病理学亚型或分子特征的变化。主要通过CT强调非代谢活性SPN随访的重要性（由于其便利性和低成本）。
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