Recombinant human decorin suppresses liver HepG2 carcinoma cells by p21 upregulation

机译：重组人得体蛋白通过p21上调抑制肝HepG2癌细胞

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BackgroundDecorin is a multifunctional molecule of the extracellular matrix and impedes different kinds of tumor cell growth, but the role and molecular mechanism by which decorin inhibits HepG2 cells is not fully understood. Our objective was to construct recombinant human decorin (pcDNA3.1-DCN) and to explore the mechanism by which it inhibits HepG2 cells.

机译：背景Decorin是细胞外基质的多功能分子，可阻止不同种类的肿瘤细胞生长，但decorin抑制HepG2细胞的作用和分子机制尚不完全清楚。我们的目的是构建重组人核心蛋白聚糖（pcDNA3.1-DCN），并探讨其抑制HepG2细胞的机制。

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期刊名称 OncoTargets and therapy
作者
Yucheng Zhang; Yali Wang; Zhenwu Du; Qian Wang; Mei Wu; Xiaofeng Wang; Lingling Wang; Linlin Cao; Abdu Selim Hamid; Guizhen Zhang;
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作者单位

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年(卷),期 2012(5),-1
年度 2012
页码 143–152
总页数 10
原文格式 PDF
正文语种
中图分类应用微生物学;肿瘤学;
关键词
decorin HepG2 liver cancer p21supWAF1/CIP1/sup pcDNA3.1;

机译：核心蛋白聚糖;HepG2;肝癌;p21 sup WAF1 / CIP1 / sup;pcDNA3.1;

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专利

1. Recombinant human decorin suppresses liver HepG2 carcinoma cells by p21 upregulation [J] . Yucheng Zhang, Yali Wang, Zhenwu Du, OncoTargets and therapy . 2012,第6期

机译：重组人得体蛋白通过p21上调抑制肝HepG2癌细胞
2. Comparison of the Structure and Biological Activities of Wild-type and Mutant Liver-targeting Peptide Modified Recombinant Human Endostatin (rES-CSP) in Human Hepatocellular Carcinoma HepG2 Cells [J] . Bao Dongmei, Jin Xiaobao, Ma Yan, Protein and peptide letters . 2015,第5期

机译：野生型和突变肝靶向肽修饰的人类内皮抑素（rES-CSP）在人肝细胞癌HepG2细胞中的结构和生物学活性的比较。
3. Recombinant human decorin upregulates P57KIP2 expression in HepG2 hepatoma cell lines [J] . HamidA.S., LiJ., WangY., Molecular medicine reports . 2013,第2期

机译：重组人得体蛋白上调HepG2肝癌细胞系中P57KIP2的表达
4. Reducible Poly(Oligo Oligo-D-Arginine) for Delivery of elivery Vascular Endothelial Growth Factor siRNAEffectively Suppresses Growth of Squamous Cell Carcinoma [C] . Young -Wook Won, Yong -Hee Kim Annual meeting exposition of the Controlled Release Society . 2009

机译：可还原的聚（Oligo Oligo-D-精氨酸）交付交付的血管内皮生长因子siRNA有效抑制鳞状细胞癌的生长。
5. The anti-cancer activities of Paeoniae Radix extracts on human hepatocellular carcinoma cell-line HepG2 and multidrug resistant human hepatocellular carcinoma cell-line R-HepG2 and their action mechanisms. [D] . Li, Lok Yee Mandy. 2004

机译：e药提取物对人肝癌细胞HepG2和多药耐药人肝癌细胞R-HepG2的抗癌活性及其作用机制。
6. 2378-Tetrachlorodibenzo-p-dioxin suppresses the growth of human liver cancer HepG2 cells in vitro: Involvement of cell signaling factors [O] . Masayoshi Yamaguchi, Oliver Hankinson -1

机译：2378-四氯二苯并-p-二恶英在体外抑制人肝癌HepG2细胞的生长：涉及细胞信号传导因子
7. Exogenous regucalcin suppresses the growth of human liver cancer HepG2 cells in vitro [O] . Masayoshi Yamaguchi, Tomiyasu Murata 2018

机译：外源性荧光蛋白在体外抑制人肝癌HepG2细胞的生长

Recombinant human decorin suppresses liver HepG2 carcinoma cells by p21 upregulation

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