首页> 美国卫生研究院文献>Nucleic Acids Research >The Cryphonectria parasitica plasmid pUG1 contains a large ORF with motifs characteristic of family B DNA polymerases.
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The Cryphonectria parasitica plasmid pUG1 contains a large ORF with motifs characteristic of family B DNA polymerases.

机译:寄生寄生虫质粒pUG1含有一个大型ORF其ORF具有B族DNA聚合酶的特征性特征。

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摘要

The isolation and characterization of the circular mitochondrial plasmid pUG1 from the ascomycete Cryphonectria parasitica is described. The entire sequence (4182 bp) was obtained and high similarities to DNA-dependent DNA polymerases were revealed. Strikingly common features with the DNA polymerases encoded by the Neurospora intermedia plasmids Fiji and LaBelle, such as matches to the conserved motifs A and B and the presence of TTD instead of DTD in motif C, were found, suggesting the existence of a distinct group of members of the B DNA family polymerases. These strong similarities between the plasmids might suggest a common origin of the C.parasitica and the Neurospora plasmids.
机译:描述了从寄生虫子囊虫的环状线粒体质粒pUG1的分离和鉴定。获得了整个序列(4182 bp),并且揭示了与DNA依赖性DNA聚合酶的高度相似性。发现了Neurospora中间质粒Fiji和LaBelle编码的DNA聚合酶的惊人共同特征,例如与保守基序A和B的匹配以及在基序C中存在TTD而不是DTD,这表明存在不同的B DNA家族聚合酶的成员。质粒之间的这些强相似性可能表明拟寄生假单胞菌和Neurospora质粒有共同的起源。

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